European Association of Urology guidelines on upper urinary tract urothelial carcinoma: 2020 update

M Rouprêt, M Babjuk, M Burger, O Capoun, D Cohen… - European urology, 2021 - Elsevier
Abstract Context The European Association of Urology (EAU) Guidelines Panel on Upper
Urinary Tract Urothelial Carcinoma (UTUC) has prepared updated guidelines to aid …

Colorectal carcinoma: a general overview and future perspectives in colorectal cancer

I Mármol, C Sánchez-de-Diego… - International journal of …, 2017 - mdpi.com
Colorectal cancer (CRC) is the third most common cancer and the fourth most common
cause of cancer-related death. Most cases of CRC are detected in Western countries, with its …

Enhanced prime editing systems by manipulating cellular determinants of editing outcomes

PJ Chen, JA Hussmann, J Yan, F Knip**… - Cell, 2021 - cell.com
While prime editing enables precise sequence changes in DNA, cellular determinants of
prime editing remain poorly understood. Using pooled CRISPRi screens, we discovered that …

ACG clinical guidelines: colorectal cancer screening 2021

A Shaukat, CJ Kahi, CA Burke… - Official journal of the …, 2021 - journals.lww.com
Colorectal cancer (CRC) is the third most common cancer in men and women in the United
States. CRC screening efforts are directed toward removal of adenomas and sessile …

The consensus molecular subtypes of colorectal cancer

J Guinney, R Dienstmann, X Wang, A De Reynies… - Nature medicine, 2015 - nature.com
Colorectal cancer (CRC) is a frequently lethal disease with heterogeneous outcomes and
drug responses. To resolve inconsistencies among the reported gene expression–based …

[HTML][HTML] Comprehensive molecular characterization of human colon and rectal cancer

Cancer Genome Atlas Network - Nature, 2012 - ncbi.nlm.nih.gov
To characterize somatic alterations in colorectal carcinoma, we conducted a genome-scale
analysis of 276 samples, analysing exome sequence, DNA copy number, promoter …

Screening and prevention of colorectal cancer

P Kanth, JM Inadomi - Bmj, 2021 - bmj.com
Mortality from colorectal cancer is reduced through screening and early detection; moreover,
removal of neoplastic lesions can reduce cancer incidence. While understanding of the risk …

[HTML][HTML] ESMO recommendations on microsatellite instability testing for immunotherapy in cancer, and its relationship with PD-1/PD-L1 expression and tumour …

C Luchini, F Bibeau, MJL Ligtenberg, N Singh… - Annals of …, 2019 - Elsevier
Background Cancers with a defective DNA mismatch repair (dMMR) system contain
thousands of mutations most frequently located in monomorphic microsatellites and are …

[BOOK][B] Applications of prediction models

EW Steyerberg, EW Steyerberg - 2009 - Springer
Applications of prediction models | SpringerLink Skip to main content Advertisement
SpringerLink Account Menu Find a journal Publish with us Track your research Search Cart …

Early‐onset colorectal cancer in young individuals

G Mauri, A Sartore‐Bianchi, AG Russo… - Molecular …, 2019 - Wiley Online Library
Treatment of young adults with colorectal cancer (CRC) represents an unmet clinical need,
especially as diagnosis in this population might lead to the greatest loss of years of life …