Local drug delivery strategies for cancer treatment: gels, nanoparticles, polymeric films, rods, and wafers

JB Wolinsky, YL Colson, MW Grinstaff - Journal of controlled release, 2012 - Elsevier
Polymer-based drug delivery depots have been investigated over the last several decades
as a means to improve upon the lack of tumor targeting and severe systemic morbidities …

Impairment‐driven cancer rehabilitation: an essential component of quality care and survivorship

JK Silver, J Baima, RS Mayer - CA: a cancer journal for …, 2013 - Wiley Online Library
Answer questions and earn CME/CNE Adult cancer survivors suffer an extremely diverse
and complex set of impairments, affecting virtually every organ system. Both physical and …

International framework for red flags for potential serious spinal pathologies

LM Finucane, A Downie, C Mercer… - journal of orthopaedic & …, 2020 - jospt.org
Synopsis The International Federation of Orthopaedic Manipulative Physical Therapists
(IFOMPT) led the development of a framework to help clinicians assess and manage people …

Predicting 90-day and 1-year mortality in spinal metastatic disease: development and internal validation

AV Karhade, QCBS Thio, PT Ogink, CM Bono… - …, 2019 - journals.lww.com
BACKGROUND Increasing prevalence of metastatic disease has been accompanied by
increasing rates of surgical intervention. Current tools have poor to fair predictive …

Assessment and management of patients with metastatic spinal cord compression: a multidisciplinary review

AJ Lawton, KA Lee, AL Cheville, ML Ferrone… - Journal of Clinical …, 2019 - ascopubs.org
Purpose Metastatic spinal cord compression (MSCC) can be a catastrophic manifestation of
advanced cancer that causes immobilizing pain and significant neurologic impairment …

A multi-resolution approach for spinal metastasis detection using deep Siamese neural networks

J Wang, Z Fang, N Lang, H Yuan, MY Su… - Computers in biology and …, 2017 - Elsevier
Spinal metastasis, a metastatic cancer of the spine, is the most common malignant disease
in the spine. In this study, we investigate the feasibility of automated spinal metastasis …

Integrating evidence-based medicine for treatment of spinal metastases into a decision framework: neurologic, oncologic, mechanicals stability, and systemic disease

O Barzilai, I Laufer, Y Yamada, DS Higginson… - Journal of clinical …, 2017 - ascopubs.org
Patients with cancer are frequently affected by spinal metastases. Treatment is palliative,
with the principle goals of pain relief, preservation of neurologic function, and improvement …

Metastatic spinal cord compression: unraveling the diagnostic and therapeutic challenges

S Boussios, D Cooke, C Hayward… - Anticancer …, 2018 - ar.iiarjournals.org
Malignant spinal cord compression (MSCC) is one of the most devastating complications of
cancer. Patients often present with a history of progressive pain, paralysis, sensory loss …

[HTML][HTML] Vertebral augmentation involving vertebroplasty or kyphoplasty for cancer-related vertebral compression fractures: a systematic review

Health Quality Ontario - Ontario health technology assessment …, 2016 - ncbi.nlm.nih.gov
Background Cancers that metastasize to the spine and primary cancers such as multiple
myeloma can result in vertebral compression fractures or instability. Conservative strategies …

Predicting survival for metastatic spine disease: a comparison of nine scoring systems

AK Ahmed, CR Goodwin, A Heravi, R Kim… - The Spine Journal, 2018 - Elsevier
Abstract Background Context Despite advances in spinal oncology, research in patient-
based prognostic calculators for metastatic spine disease is lacking. Much of the literature in …