In the last decade, hyaluronic acid (HA) has attracted an ever-growing interest in the
biomedical engineering field as a biocompatible, biodegradable, and chemically versatile …

Nestorone®(segesterone acetate) is a progestin with a chemical structure closely related to
progesterone with high affinity and selectivity for the progesterone receptor without …

Traumatic brain injury (TBI) is one of the most common causes of neurological damage in
young human populations. Vitamin B12 has been reported to promote axon growth of …

Multiple sclerosis (MS) is a highly heterogeneous disease with varying remyelination
potential across individuals and between lesions. However, the molecular mechanisms …

During differentiation, oligodendrocyte precursor cells (OPCs) extend a network of
processes that make contact with axons and initiate myelination. Recent studies revealed …

Hormone therapy, primarily progesterone and progestins, for central nervous system (CNS)
disorders represents an emerging field of regenerative medicine. Following a failed clinical …

The lack of regenerative solutions for demyelination within the central nervous system
motivates the development of strategies to expand and drive the bioactivity of the cells …

Multiple Sclerosis (MS) causes neurologic disability due to inflammation, demyelination, and
neurodegeneration. Immunosuppressive treatments can modify the disease course but do …

Current treatments in multiple sclerosis (MS) are modulating the inflammatory component of
the disease, but no drugs are currently available to repair lesions. Our study identifies in MS …

Hypomyelinating leukodystrophy 7 (HLD7) is an autosomal recessive oligodendroglial cell-
related myelin disease, which is associated with some nucleotide mutations of the RNA …