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Polymerization of ethylene oxide, propylene oxide, and other alkylene oxides: synthesis, novel polymer architectures, and bioconjugation
The review summarizes current trends and developments in the polymerization of alkylene
oxides in the last two decades since 1995, with a particular focus on the most important …
oxides in the last two decades since 1995, with a particular focus on the most important …
Polymeric mixed micelles as nanomedicines: Achievements and perspectives
M Cagel, FC Tesan, E Bernabeu, MJ Salgueiro… - European Journal of …, 2017 - Elsevier
During the past few decades, polymeric micelles have raised special attention as novel
nano-sized drug delivery systems for optimizing the treatment and diagnosis of numerous …
nano-sized drug delivery systems for optimizing the treatment and diagnosis of numerous …
Poloxamers, poloxamines and polymeric micelles: Definition, structure and therapeutic applications in cancer
Research for new therapies to treat diseases like cancer, it is one of the focus of Health
Sciences. Nowadays, the available therapeutic strategies have in many cases limitations …
Sciences. Nowadays, the available therapeutic strategies have in many cases limitations …
Supramolecular cyclodextrin-based drug nanocarriers
Supramolecular systems formed by the binding of several cyclodextrins (CDs) to polymers or
lipids, either via non-covalent or covalent links, open a wide range of possibilities for the …
lipids, either via non-covalent or covalent links, open a wide range of possibilities for the …
Polymeric micelles in mucosal drug delivery: Challenges towards clinical translation
A Sosnik, MM Raskin - Biotechnology advances, 2015 - Elsevier
Polymeric micelles are nanostructures formed by the self-aggregation of copolymeric
amphiphiles above the critical micellar concentration. Due to the flexibility to tailor different …
amphiphiles above the critical micellar concentration. Due to the flexibility to tailor different …
α-Lipoic acid in Soluplus® polymeric nanomicelles for ocular treatment of diabetes-associated corneal diseases
F Alvarez-Rivera, D Fernández-Villanueva… - Journal of …, 2016 - Elsevier
Abstract α-Lipoic acid (ALA) is a powerful antioxidant valuable for prevention and treatment
of ophthalmic complications such as diabetic keratopathy and retinopathy. The aim of this …
of ophthalmic complications such as diabetic keratopathy and retinopathy. The aim of this …
Efavirenz-loaded polymeric micelles for pediatric anti-HIV pharmacotherapy with significantly higher oral bioavailability
DA Chiappetta, C Hocht, C Taira, A Sosnik - Nanomedicine, 2010 - Taylor & Francis
Children constitute the most challenging population in anti-HIV/AIDS pharmacotherapy.
Efavirenz (EFV; aqueous solubility 4 µg/ml, bioavailability 40–45%) is a first-line agent in the …
Efavirenz (EFV; aqueous solubility 4 µg/ml, bioavailability 40–45%) is a first-line agent in the …
In situ forming hydrogels based on tyramine conjugated 4-Arm-PPO-PEO via enzymatic oxidative reaction
Over the past decades, hydrogels have been widely studied as biomaterials for various
biomedical applications like implants, drugs and cell delivery carriers because of their high …
biomedical applications like implants, drugs and cell delivery carriers because of their high …
[HTML][HTML] PEO-PPO-PEO tri-block copolymers for gene delivery applications in human regenerative medicine—an overview
Lineal (poloxamers or Pluronic®) or X-shaped (poloxamines or Tetronic®) amphiphilic tri-
block copolymers of poly (ethylene oxide) and poly (propylene oxide)(PEO-PPO-PEO) have …
block copolymers of poly (ethylene oxide) and poly (propylene oxide)(PEO-PPO-PEO) have …
PEO-PPO block copolymers for passive micellar targeting and overcoming multidrug resistance in cancer therapy
Drug carriers tailored to fit the physicochemical properties of anticancer agents and the
therapeutic peculiarities of tumor management are envisioned for improving the …
therapeutic peculiarities of tumor management are envisioned for improving the …