[HTML][HTML] Current approaches of nanomedicines in the market and various stage of clinical translation

X Shan, X Gong, J Li, J Wen, Y Li, Z Zhang - Acta Pharmaceutica Sinica B, 2022 - Elsevier
Compared with traditional drug therapy, nanomedicines exhibit intriguing biological features
to increase therapeutic efficiency, reduce toxicity and achieve targeting delivery. This review …

The next-generation DNA vaccine platforms and delivery systems: advances, challenges and prospects

B Lu, JM Lim, B Yu, S Song, P Neeli… - Frontiers in …, 2024 - frontiersin.org
Vaccines have proven effective in the treatment and prevention of numerous diseases.
However, traditional attenuated and inactivated vaccines suffer from certain drawbacks such …

MBD2 serves as a viable target against pulmonary fibrosis by inhibiting macrophage M2 program

Y Wang, L Zhang, GR Wu, Q Zhou, H Yue, LZ Rao… - Science …, 2021 - science.org
Despite past extensive studies, the mechanisms underlying pulmonary fibrosis (PF) still
remain poorly understood. Here, we demonstrated that lungs originating from different types …

Inhalable nanoparticle-based dry powder formulations for respiratory diseases: challenges and strategies for translational research

HW Chan, S Chow, X Zhang, Y Zhao, HHY Tong… - AAPS …, 2023 - Springer
The emergence of novel respiratory infections (eg, COVID-19) and expeditious development
of nanoparticle-based COVID-19 vaccines have recently reignited considerable interest in …

Aerosolized Nanoliposomal Carrier of Remdesivir: An Effective Alternative for COVID-19 Treatment In Vitro

R Vartak, SM Patil, A Saraswat, M Patki, NK Kunda… - …, 2021 - Taylor & Francis
Aim: To formulate an aerosolized nanoliposomal carrier for remdesivir (AL-Rem) against
coronavirus disease 2019. Methods: AL-Rem was prepared using modified hydration …

Increasing complexity and interactions of oxidative stress in chronic respiratory diseases: An emerging need for novel drug delivery systems

K Dua, V Malyla, G Singhvi, R Wadhwa… - Chemico-biological …, 2019 - Elsevier
Oxidative stress is intensely involved in enhancing the severity of various chronic respiratory
diseases (CRDs) including asthma, chronic obstructive pulmonary disease (COPD) …

Protein nanoparticles as drug delivery systems for cancer theranostics

Y Hua, Z Qin, L Gao, M Zhou, Y Xue, Y Li… - Journal of Controlled …, 2024 - Elsevier
Protein-based nanoparticles have garnered significant attention in theranostic applications
due to their superior biocompatibility, exceptional biodegradability and ease of functionality …

[HTML][HTML] Impact of phospholipids, surfactants and cholesterol selection on the performance of transfersomes vesicles using medical nebulizers for pulmonary drug …

I Khan, R Needham, S Yousaf, C Houacine… - Journal of Drug Delivery …, 2021 - Elsevier
The aim of this study is to formulate and optimize novel transfersome formulations for
pulmonary drug delivery. Transfersome formulations (F1–F18) were prepared by a thin-film …

Research and development of drug delivery systems based on drug transporter and nano-formulation

Y Peng, L Chen, S Ye, Y Kang, J Liu, S Zeng… - Asian journal of …, 2020 - Elsevier
In recent years, the continuous occurrence of multi-drug resistance in the clinic has made
people pay more attention to the transporter. Changes in the expression and activity of …

[HTML][HTML] Anticancer drug delivery: Investigating the impacts of viscosity on lipid-based formulations for pulmonary targeting

AM Thevarkattil, S Yousaf, C Houacine, W Khan… - International Journal of …, 2024 - Elsevier
Pulmonary drug delivery via aerosolization is a non-intrusive method for achieving localized
and systemic effects. The aim of this study was to establish the impact of viscosity as a novel …