Tourette syndrome: clinical features, pathophysiology, and treatment

KA Johnson, Y Worbe, KD Foote, CR Butson… - The Lancet …, 2023 - thelancet.com
Tourette syndrome is a chronic neurodevelopmental disorder characterised by motor and
phonic tics that can substantially diminish the quality of life of affected individuals. Evaluating …

Practice guideline recommendations summary: treatment of tics in people with Tourette syndrome and chronic tic disorders

T Pringsheim, MS Okun, K Müller-Vahl, D Martino… - Neurology, 2019 - neurology.org
Objective To make recommendations on the assessment and management of tics in people
with Tourette syndrome and chronic tic disorders. Methods A multidisciplinary panel …

Deep brain stimulation in movement disorders: from experimental surgery to evidence‐based therapy

P Krack, J Volkmann, G Tinkhauser… - Movement …, 2019 - Wiley Online Library
Deep brain stimulation (DBS) of 3 different targets is the most important therapeutic
innovation of the past 30 years for patients with fluctuating Parkinson's disease (PD) …

Biomarkers for closed-loop deep brain stimulation in Parkinson disease and beyond

W Bouthour, P Mégevand, J Donoghue… - Nature Reviews …, 2019 - nature.com
Subthalamic deep brain stimulation (DBS) for Parkinson disease (PD) currently requires
laborious open-loop programming, which can mitigate the benefits of this treatment …

[HTML][HTML] A comprehensive review of tic disorders in children

K Ueda, KJ Black - Journal of clinical medicine, 2021 - mdpi.com
Tics are characterized by sudden, rapid, recurrent, nonrhythmic movement or vocalization,
and are the most common movement disorders in children. Their onset is usually in …

Tissue response to neural implants: the use of model systems toward new design solutions of implantable microelectrodes

M Gulino, D Kim, S Pané, SD Santos… - Frontiers in …, 2019 - frontiersin.org
The development of implantable neuroelectrodes is advancing rapidly as these tools are
becoming increasingly ubiquitous in clinical practice, especially for the treatment of …

[HTML][HTML] Toward electrophysiology-based intelligent adaptive deep brain stimulation for movement disorders

WJ Neumann, RS Turner, B Blankertz, T Mitchell… - …, 2019 - Elsevier
Deep brain stimulation (DBS) represents one of the major clinical breakthroughs in the age
of translational neuroscience. In 1987, Benabid and colleagues demonstrated that high …

A neural network for tics: insights from causal brain lesions and deep brain stimulation

C Ganos, B Al-Fatly, JF Fischer, JC Baldermann… - Brain, 2022 - academic.oup.com
Brain lesions are a rare cause of tic disorders. However, they can provide uniquely causal
insights into tic pathophysiology and can also inform on possible neuromodulatory …

Tourette's syndrome

J Jankovic - New England Journal of Medicine, 2001 - Mass Medical Soc
The French neurologist Georges Gilles de la Tourette first described this syndrome, which
consists of motor tics sometimes accompanied by uncontrollable noises or utterances …

[HTML][HTML] Current management of tics and Tourette syndrome: behavioral, pharmacologic, and surgical treatments

A Billnitzer, J Jankovic - Neurotherapeutics, 2020 - Elsevier
Tourette syndrome is a heterogeneous neurobehavioral disorder manifested by childhood-
onset motor and phonic tics, often accompanied by a variety of behavioral comorbidities …