[HTML][HTML] Mesenchymal chondrosarcoma from diagnosis to clinical trials

M Dudzisz-Śledź, M Kondracka, M Rudzińska… - Cancers, 2023 - mdpi.com
Simple Summary Mesenchymal chondrosarcoma (MCS) is a subtype of chondrosarcoma
with rare occurrence and poor survival rates. MCS stains positive for S-100 and SOX9 as …

Decoding cancer etiology with cellular reprogramming

MF Huang, ME Fisher, TTT Phan, R Zhao… - Current Opinion in …, 2025 - Elsevier
Cancer research remains clinically unmet in many areas due to limited access to patient
samples and the lack of reliable model systems that truly reflect human cancer biology. The …

Uncovering the WWTR1::NCOA2 Gene fusion in low‐grade myoepithelial‐rich neoplasm with HMGA2 expression: A case report

Z Alsugair, D Pissaloux, F Descotes… - Genes …, 2024 - Wiley Online Library
We describe a case of a pleomorphic adenoma (PA) arising from the para‐tracheal
accessory salivary gland in a 44‐year‐old male harboring a novel WWTR1:: NCOA2 gene …

Real‐world experience of tyrosine kinase inhibitors in children, adolescents and adults with relapsed or refractory bone tumours: A Canadian Sarcoma Research and …

H Peretz Soroka, T Vora, J Noujaim… - Cancer …, 2023 - Wiley Online Library
Objectives We conducted a retrospective multi‐centre study to assess the real‐world
outcome of regorafenib (REGO) and cabozantinib (CABO) in recurrent/refractory bone …

[HTML][HTML] Chondrosarcoma: New Molecular Insights, Challenges in Near-Patient Preclinical Modeling, and Therapeutic Approaches

L Landuzzi, F Ruzzi, PL Lollini, K Scotlandi - International Journal of …, 2025 - mdpi.com
Chondrosarcoma (CS), the second most common malignant bone tumor after osteosarcoma,
accounts for 20–30% of all malignant bone tumors. It mainly affects adults, middle-aged, and …

Myoepithelial carcinoma of the parotid gland with a novel CTCF::NCOA2 fusion

J Gandhi, JG Mantilla, RW Ricciotti… - Genes …, 2023 - Wiley Online Library
We describe a case of a myoepithelial carcinoma of the superficial parotid gland in a 46‐
year‐old male harboring a novel CTCF:: NCOA2 gene fusion. To our knowledge, this novel …

Metastatic mesenchymal chondrosarcoma showing a sustained response to cabozantinib: A case report

V Blum, V Andrei, B Ameline, S Hofer, B Fuchs… - Frontiers in …, 2022 - frontiersin.org
Mesenchymal chondrosarcoma is a rare and aggressive sarcoma subtype with high risk for
distant metastases and poor prognosis. Currently NCCN-and ESMO-Guidelines recommend …

Targeted RNA sequencing in diagnostically challenging head and neck carcinomas identifies novel MON2:: STAT6, NFATC2:: NUTM2B, POC5:: RAF1, and NSD3 …

YH Chu, N Katabi, P Sukhadia, KA Mullaney… - …, 2024 - Wiley Online Library
Aims Although molecular tests developed for a growing list of oncogenic alterations have
significantly aided in the classification of head and neck carcinomas, tumours in which …

Cartilage Forming Tumors of the Skeleton

JA Diaz-Perez, AE Rosenberg - Advances in anatomic pathology, 2024 - journals.lww.com
Cartilage-forming tumors are a broad and diverse group of neoplasms frequently affecting
the skeleton. Distinguishing between the members of this group is important because of …

Case report: A mesenchymal chondrosarcoma with alternative HEY1:: NCOA2 fusions in the sella turcica

S Kishikawa, A Kondo, T Yao, T Saito - Pathology and Oncology …, 2024 - por-journal.com
Introduction Mesenchymal chondrosarcoma (MCS) is a rare subtype of chondrosarcoma that
occurs at widespread anatomical locations, such as bone, soft tissue, and intracranial sites …