[HTML][HTML] Pharmaceutical amorphous solid dispersion: A review of manufacturing strategies
Amorphous solid dispersions (ASDs) are popular for enhancing the solubility and
bioavailability of poorly water-soluble drugs. Various approaches have been employed to …
bioavailability of poorly water-soluble drugs. Various approaches have been employed to …
Amorphous solid dispersions: Rational selection of a manufacturing process
Amorphous products and particularly amorphous solid dispersions are currently one of the
most exciting areas in the pharmaceutical field. This approach presents huge potential and …
most exciting areas in the pharmaceutical field. This approach presents huge potential and …
Current trends and future perspectives of solid dispersions containing poorly water-soluble drugs
Over 40% of active pharmaceutical ingredients (API) in development pipelines are poorly
water-soluble drugs which limit formulation approaches, clinical application and …
water-soluble drugs which limit formulation approaches, clinical application and …
Solid dispersions as strategy to improve oral bioavailability of poor water soluble drugs
Solid dispersions are one of the most promising strategies to improve the oral bioavailability
of poorly water soluble drugs. By reducing drug particle size to the absolute minimum, and …
of poorly water soluble drugs. By reducing drug particle size to the absolute minimum, and …
Eutectic mixtures as an approach to enhance solubility, dissolution rate and oral bioavailability of poorly water-soluble drugs
Eutectic mixtures have been known for a long time in the pharmaceutical field. However, its
potential as a system to improve the solubility and dissolution of poorly water-soluble drugs …
potential as a system to improve the solubility and dissolution of poorly water-soluble drugs …
Preparation and evaluation of nanosuspensions for enhancing the dissolution of poorly soluble drugs
Poorly water-soluble compounds are difficult to develop as drug products using
conventional formulation techniques and are frequently abandoned early in discovery. In the …
conventional formulation techniques and are frequently abandoned early in discovery. In the …
The preparation of orally disintegrating tablets using a hydrophilic waxy binder
G Abdelbary, P Prinderre, C Eouani, J Joachim… - International journal of …, 2004 - Elsevier
The demand for rapidly disintegrating tablets (RDT) has been growing during the last
decade especially for elderly and children who have swallowing difficulties. The problem of …
decade especially for elderly and children who have swallowing difficulties. The problem of …
Preparation, characterization and in vivo evaluation of ibuprofen binary solid dispersions with poloxamer 188
M Newa, KH Bhandari, DX Li, TH Kwon, JA Kim… - International journal of …, 2007 - Elsevier
Ibuprofen–Poloxamer 188 (P 188) binary solid dispersions (SD) with different drug loadings
were prepared, characterized by scanning electron microscopy (SEM), differential scanning …
were prepared, characterized by scanning electron microscopy (SEM), differential scanning …
[HTML][HTML] Classification of scanning electron microscope images of pharmaceutical excipients using deep convolutional neural networks with transfer learning
Abstract Convolutional Neural Networks (CNNs) are image analysis techniques that have
been applied to image classification in various fields. In this study, we applied a CNN to …
been applied to image classification in various fields. In this study, we applied a CNN to …
Evaluation of melt granulation and ultrasonic spray congealing as techniques to enhance the dissolution of praziquantel
N Passerini, B Albertini, B Perissutti… - International journal of …, 2006 - Elsevier
Praziquantel (PZQ), an anthelminthic drug widely used in develo** countries, is classified
in Class II in the Biopharmaceutics Classification Systems; this means that PZQ has very low …
in Class II in the Biopharmaceutics Classification Systems; this means that PZQ has very low …