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Physiological adaptations to low‐volume, high‐intensity interval training in health and disease
Exercise training is a clinically proven, cost‐effective, primary intervention that delays and in
many cases prevents the health burdens associated with many chronic diseases. However …
many cases prevents the health burdens associated with many chronic diseases. However …
Molecular mechanisms of exercise contributing to tissue regeneration
J Chen, R Zhou, Y Feng, L Cheng - Signal Transduction and Targeted …, 2022 - nature.com
Physical activity has been known as an essential element to promote human health for
centuries. Thus, exercise intervention is encouraged to battle against sedentary lifestyle …
centuries. Thus, exercise intervention is encouraged to battle against sedentary lifestyle …
Principles of exercise prescription, and how they influence exercise-induced changes of transcription factors and other regulators of mitochondrial biogenesis
Physical inactivity represents the fourth leading risk factor for mortality, and it has been
linked with a series of chronic disorders, the treatment of which absorbs~ 85% of healthcare …
linked with a series of chronic disorders, the treatment of which absorbs~ 85% of healthcare …
Metabolic control through the PGC-1 family of transcription coactivators
Many complex biological programs are controlled at the level of gene transcription by DNA
binding transcription factors. Recent studies have revealed a novel mode of regulation by …
binding transcription factors. Recent studies have revealed a novel mode of regulation by …
PGC-1α: a key regulator of energy metabolism
H Liang, WF Ward - Advances in physiology education, 2006 - journals.physiology.org
Peroxisome proliferator-activated receptor-γ coactivator (PGC)-1α is a member of a family of
transcription coactivators that plays a central role in the regulation of cellular energy …
transcription coactivators that plays a central role in the regulation of cellular energy …
Reactive oxygen species: impact on skeletal muscle
It is well established that contracting muscles produce both reactive oxygen and nitrogen
species. Although the sources of oxidant production during exercise continue to be debated …
species. Although the sources of oxidant production during exercise continue to be debated …
Repeated transient mRNA bursts precede increases in transcriptional and mitochondrial proteins during training in human skeletal muscle
Exercise training induces mitochondrial biogenesis, but the time course of molecular
sequelae that accompany repetitive training stimuli remains to be determined in human …
sequelae that accompany repetitive training stimuli remains to be determined in human …
[HTML][HTML] AMPK and PPARδ agonists are exercise mimetics
The benefits of endurance exercise on general health make it desirable to identify orally
active agents that would mimic or potentiate the effects of exercise to treat metabolic …
active agents that would mimic or potentiate the effects of exercise to treat metabolic …
The molecular bases of training adaptation
Skeletal muscle is a malleable tissue capable of altering the type and amount of protein in
response to disruptions to cellular homeostasis. The process of exerciseinduced adaptation …
response to disruptions to cellular homeostasis. The process of exerciseinduced adaptation …
[HTML][HTML] Irisin acts through its integrin receptor in a two-step process involving extracellular Hsp90α
Exercise benefits the human body in many ways. Irisin is secreted by muscle, increased with
exercise, and conveys physiological benefits, including improved cognition and resistance …
exercise, and conveys physiological benefits, including improved cognition and resistance …