Fundamentals of redox regulation in biology

H Sies, RJ Mailloux, U Jakob - Nature Reviews Molecular Cell Biology, 2024 - nature.com
Oxidation–reduction (redox) reactions are central to the existence of life. Reactive species of
oxygen, nitrogen and sulfur mediate redox control of a wide range of essential cellular …

Malondialdehyde as a potential oxidative stress marker for allergy-oriented diseases: an update

R Cordiano, M Di Gioacchino, R Mangifesta… - Molecules, 2023 - mdpi.com
Malondialdehyde (MDA) is a compound that is derived from the peroxidation of
polyunsaturated fatty acids. It has been used as a biomarker to measure oxidative stress in …

Defining roles of specific reactive oxygen species (ROS) in cell biology and physiology

H Sies, VV Belousov, NS Chandel, MJ Davies… - … reviews Molecular cell …, 2022 - nature.com
Abstract 'Reactive oxygen species'(ROS) is a generic term that defines a wide variety of
oxidant molecules with vastly different properties and biological functions that range from …

Oxidative stress in cancer cell metabolism

S Arfin, NK Jha, SK Jha, KK Kesari, J Ruokolainen… - Antioxidants, 2021 - mdpi.com
Reactive oxygen species (ROS) are important in regulating normal cellular processes
whereas deregulated ROS leads to the development of a diseased state in humans …

Endothelial dysfunction due to eNOS uncoupling: molecular mechanisms as potential therapeutic targets

A Janaszak-Jasiecka, A Płoska, JM Wierońska… - Cellular & molecular …, 2023 - Springer
Nitric oxide (NO) is one of the most important molecules released by endothelial cells, and
its antiatherogenic properties support cardiovascular homeostasis. Diminished NO …

[HTML][HTML] Overview of the mechanisms of oxidative stress: impact in inflammation of the airway diseases

GD Albano, RP Gagliardo, AM Montalbano, M Profita - Antioxidants, 2022 - mdpi.com
Inflammation of the human lung is mediated in response to different stimuli (eg, physical,
radioactive, infective, pro-allergenic or toxic) such as cigarette smoke and environmental …

Reactive oxygen species (ROS) as pleiotropic physiological signalling agents

H Sies, DP Jones - Nature reviews Molecular cell biology, 2020 - nature.com
Abstract 'Reactive oxygen species'(ROS) is an umbrella term for an array of derivatives of
molecular oxygen that occur as a normal attribute of aerobic life. Elevated formation of the …

Antioxidant and anti-tumor effects of dietary vitamins A, C, and E

AJ Didier, J Stiene, L Fang, D Watkins, LD Dworkin… - Antioxidants, 2023 - mdpi.com
Oxidative stress, a condition characterized by an imbalance between pro-oxidant molecules
and antioxidant defense systems, is increasingly recognized as a key contributor to cancer …

Signaling pathways in vascular function and hypertension: molecular mechanisms and therapeutic interventions

J Ma, Y Li, X Yang, K Liu, X Zhang, X Zuo… - Signal transduction and …, 2023 - nature.com
Hypertension is a global public health issue and the leading cause of premature death in
humans. Despite more than a century of research, hypertension remains difficult to cure due …