A comprehensive survey upon diverse and prolific applications of chitosan-based catalytic systems in one-pot multi-component synthesis of heterocyclic rings

H Mousavi - International Journal of Biological Macromolecules, 2021 - Elsevier
Heterocyclic compounds are among the most prestigious and valuable chemical molecules
with diverse and magnificent applications in various sciences. Due to the remarkable and …

Microwave-Assisted Synthesis of Six-Membered O-Heterocycles

N Kaur, D Kishore - Synthetic Communications, 2014 - Taylor & Francis
The development of new strategies for synthesis of six-membered O-heterocycles has
remained a highly attractive but challenging proposition. An overview of the application of …

Mechanochemical synthesis and molecular docking studies of new azines bearing indole as anticancer agents

MS Ibrahim, B Farag, J Y. Al-Humaidi, MEA Zaki… - Molecules, 2023 - mdpi.com
The development of new approaches for the synthesis of new bioactive heterocyclic
derivatives is of the utmost importance for pharmaceutical industry. In this regard, the …

One-pot synthesis of novel thiazoles as potential anti-cancer agents

AR Sayed, SM Gomha, EA Taher… - Drug design …, 2020 - Taylor & Francis
Background Thiazole and thiosemicarbazone derivatives are known to have potential
anticancer activity with a mechanism of action related to inhibition of matrix metallo …

Clean grinding technique: A facile synthesis and in silico antiviral activity of hydrazones, pyrazoles, and pyrazines bearing thiazole moiety against SARS-CoV-2 main …

S Abu-Melha, MM Edrees, SM Riyadh, MR Abdelaziz… - Molecules, 2020 - mdpi.com
A novel series of some hydrazones bearing thiazole moiety were generated via solvent-drop
grinding of thiazole carbohydrazide 2 with various carbonyl compounds. Also, dehydrative …

[HTML][HTML] Green synthesis and molecular docking study of some new thiazoles using terephthalohydrazide chitosan hydrogel as ecofriendly biopolymeric catalyst

JY Al-Humaidi, SM Gomha, NAA El-Ghany, B Farag… - Catalysts, 2023 - mdpi.com
Terephthalohydrazide chitosan hydrogel (TCs) was prepared and investigated as an
ecofriendly biopolymeric catalyst for synthesis of some novel thiazole and thiadiazole …

A green synthesis, DFT calculations, and molecular docking study of some new indeno [2, 1-b] quinoxalines containing thiazole moiety

AM Abdallah, SM Gomha, MEA Zaki… - Journal of Molecular …, 2023 - Elsevier
A series of new indenoquinoxaline-thiazole hybrids were synthesized by combining
indenoquinoxaline thiosemicarbazone with appropriate hydrazonoyl chlorides or α-halo …

Green biocatalyst for ultrasound-assisted thiazole derivatives: synthesis, antibacterial evaluation, and docking analysis

AM Hussein, SM Gomha, NAA El-Ghany, MEA Zaki… - ACS …, 2024 - ACS Publications
The catalytic activity of chitosan (Cs) and grafted Cs led to the preparation of
terephthalohydrazide Cs Schiff's base hydrogel (TCsSB), which was then investigated as an …

New pyrazoles incorporating pyrazolylpyrazole moiety: Synthesis, anti-HCV and antitumor activity

SM Riyadh, TA Farghaly, MA Abdallah… - European journal of …, 2010 - Elsevier
Three series of novel pyrazole derivatives 2b–d, 4a–d and 6a–d were synthesized via two
step procedure that utilizes hydrazonoyl chlorides 1a–d and enaminones 3a–d and 5a–d …

Synthesis, In vitro and In silico Studies of Novel Bis‐triazolopyridopyrimidines from Curcumin Analogues as Potential Aromatase Agents

SM Gomha, AAAA El‐Sayed, MEA Zaki… - Chemistry & …, 2024 - Wiley Online Library
Breast cancer remains a major global health issue, particularly affecting women and
contributing significantly to mortality rates. Current treatments for estrogen receptor‐positive …