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2022 AHA/ACC/HFSA guideline for the management of heart failure: a report of the American College of Cardiology/American Heart Association Joint Committee on …
Abstract Aim The “2022 AHA/ACC/HFSA Guideline for the Management of Heart Failure”
replaces the “2013 ACCF/AHA Guideline for the Management of Heart Failure” and the …
replaces the “2013 ACCF/AHA Guideline for the Management of Heart Failure” and the …
Chemotherapy side-effects: not all DNA damage is equal
WMC van den Boogaard, DSJ Komninos, WP Vermeij - Cancers, 2022 - mdpi.com
Simple Summary The number of children and adults with cancer that are completely cured is
still increasing thanks to effective anti-cancer therapy, but they may be confronted with the …
still increasing thanks to effective anti-cancer therapy, but they may be confronted with the …
Doxorubicin prodrug-based nanomedicines for the treatment of cancer
H Zhao, J Yu, R Zhang, P Chen, H Jiang… - European journal of …, 2023 - Elsevier
The chemotherapeutic drug of doxorubicin (DOX) has witnessed widespread applications
for treating various cancers. DOX-treated dying cells bear cellular modifications which allow …
for treating various cancers. DOX-treated dying cells bear cellular modifications which allow …
Cardiotoxicity of anticancer drugs: molecular mechanisms and strategies for cardioprotection
MB Morelli, C Bongiovanni, S Da Pra… - Frontiers in …, 2022 - frontiersin.org
Chemotherapy and targeted therapies have significantly improved the prognosis of
oncology patients. However, these antineoplastic treatments may also induce adverse …
oncology patients. However, these antineoplastic treatments may also induce adverse …
Contribution to tumor angiogenesis from innate immune cells within the tumor microenvironment: implications for immunotherapy
The critical role of angiogenesis in promoting tumor growth and metastasis is strongly
established. However, tumors show considerable variation in angiogenic characteristics and …
established. However, tumors show considerable variation in angiogenic characteristics and …
Molecular mechanism involved in cyclophosphamide-induced cardiotoxicity: Old drug with a new vision
Cyclophosphamide (CP) is an important anticancer drug which belongs to the class of
alkylating agent. Cyclophosphamide is mostly used in bone marrow transplantation …
alkylating agent. Cyclophosphamide is mostly used in bone marrow transplantation …
Breast cancer survivorship: a comprehensive review of long-term medical issues and lifestyle recommendations
BI Bodai, P Tuso - The Permanente Journal, 2015 - pmc.ncbi.nlm.nih.gov
Long-term survival rates after a diagnosis of breast cancer are steadily rising. This is good
news, but clinicians must also recognize that this brings new challenges to the medical …
news, but clinicians must also recognize that this brings new challenges to the medical …
Systematic analysis of drug-associated myocarditis reported in the World Health Organization pharmacovigilance database
While multiple pharmacological drugs have been associated with myocarditis, temporal
trends and overall mortality have not been reported. Here we report the spectrum and main …
trends and overall mortality have not been reported. Here we report the spectrum and main …
Anthracycline-induced cardiotoxicity in the chemotherapy treatment of breast cancer: Preventive strategies and treatment
F Cai, MAF Luis, X Lin, M Wang… - Molecular and …, 2019 - spandidos-publications.com
Anthracyclines are highly effective chemotherapeutic agents, used for a wide variety of
malignancies. Cardiotoxicity is a well-recognized side effect of anthracycline therapy that …
malignancies. Cardiotoxicity is a well-recognized side effect of anthracycline therapy that …
Cancer-activated doxorubicin prodrug nanoparticles induce preferential immune response with minimal doxorubicin-related toxicity
The effective chemotherapeutic drug, doxorubicin (DOX), elicits immunogenic cell death
(ICD) and additional anticancer immune responses during chemotherapy. However, it also …
(ICD) and additional anticancer immune responses during chemotherapy. However, it also …