The tubulin code and its role in controlling microtubule properties and functions
C Janke, MM Magiera - Nature Reviews Molecular Cell Biology, 2020 - nature.com
Microtubules are core components of the eukaryotic cytoskeleton with essential roles in cell
division, sha**, motility and intracellular transport. Despite their functional heterogeneity …
division, sha**, motility and intracellular transport. Despite their functional heterogeneity …
The tubulin code in microtubule dynamics and information encoding
A Roll-Mecak - Developmental cell, 2020 - cell.com
Microtubules are non-covalent mesoscale polymers central to the eukaryotic cytoskeleton.
Microtubule structure, dynamics, and mechanics are modulated by a cell's choice of tubulin …
Microtubule structure, dynamics, and mechanics are modulated by a cell's choice of tubulin …
Mechanosensitive ion channels: structural features relevant to mechanotransduction mechanisms
P **, LY Jan, YN Jan - Annual review of neuroscience, 2020 - annualreviews.org
Activation of mechanosensitive ion channels underlies a variety of fundamental
physiological processes that require sensation of mechanical force. Different …
physiological processes that require sensation of mechanical force. Different …
[HTML][HTML] Microtubule control of functional architecture in neurons
MT Kelliher, HAJ Saunders, J Wildonger - Current opinion in neurobiology, 2019 - Elsevier
Highlights•Regulation of non-centrosomal microtubule organization in neurons.•Role of
resilient acetylated microtubules in mechanosensation.•Patterning microtubule tracks to …
resilient acetylated microtubules in mechanosensation.•Patterning microtubule tracks to …
Tubulin post-translational modifications: the elusive roles of acetylation
Simple Summary Microtubules (MTs) are dynamic structures that compose part of the cell
cytoskeleton. They play important roles in various cellular functions, such as intracellular …
cytoskeleton. They play important roles in various cellular functions, such as intracellular …
Tubulin post‐translational modifications control neuronal development and functions
MJ Moutin, C Bosc, L Peris… - Developmental …, 2021 - Wiley Online Library
Microtubules (MTs) are an essential component of the neuronal cytoskeleton; they are
involved in various aspects of neuron development, maintenance, and functions including …
involved in various aspects of neuron development, maintenance, and functions including …
Force from filaments: the role of the cytoskeleton and extracellular matrix in the gating of mechanosensitive channels
The senses of proprioception, touch, hearing, and blood pressure on mechanosensitive ion
channels that transduce mechanical stimuli with high sensitivity and speed. This conversion …
channels that transduce mechanical stimuli with high sensitivity and speed. This conversion …
Acetylated α-tubulin K394 regulates microtubule stability to shape the growth of axon terminals
HAJ Saunders, DM Johnson-Schlitz, BV Jenkins… - Current Biology, 2022 - cell.com
Microtubules are essential to neuron shape and function. Acetylation of tubulin has the
potential to directly tune the behavior and function of microtubules in cells. Although …
potential to directly tune the behavior and function of microtubules in cells. Although …
Cardiomyocyte microtubules: control of mechanics, transport, and remodeling
K Uchida, EA Scarborough… - Annual review of …, 2022 - annualreviews.org
Microtubules are essential cytoskeletal elements found in all eukaryotic cells. The structure
and composition of microtubules regulate their function, and the dynamic remodeling of the …
and composition of microtubules regulate their function, and the dynamic remodeling of the …
Mechanical forces orchestrate brain development
During brain development, progenitors generate successive waves of neurons that populate
distinct cerebral regions, where they settle and differentiate within layers or nuclei. While …
distinct cerebral regions, where they settle and differentiate within layers or nuclei. While …