Transdermal drug delivery systems

V Kumar, N Praveen, P Kewlani, Arvind… - Advanced Drug Delivery …, 2023 - Springer
The transdermal drug delivery systems, also known as TDDS, are the most effective
alternative to the oral and parenteral routes to deliver therapeutic molecules across the skin …

[PDF][PDF] Transdermal drug delivery system: a review

A Arunachalam, M Karthikeyan, DV Kumar… - Journal of Current …, 2010 - academia.edu
The transdermal route has numerous advantages over the more traditional drug delivery
routes. These include high bioavailability, absence of first pass hepatic metabolism, steady …

Central composite design for the development of carvedilol-loaded transdermal ethosomal hydrogel for extended and enhanced anti-hypertensive effect

PR Amarachinta, G Sharma, N Samed… - Journal of …, 2021 - Springer
Background Carvedilol, the anti-hypertensive drug, has poor bioavailability when
administered orally. Ethosomes-mediated transdermal delivery is considered a potential …

[PDF][PDF] Blooming pharma industry with transdermal drug delivery system

N Sharma, B Parashar, S Sharma… - Indo Global Journal of …, 2012 - academia.edu
The human skin is a readily accessible surface for drug delivery. It is one of the most readily
accessible organs of the human body. The potential of using the intact skin as the port of …

Preparation and characterization of ivabradine HCl transfersomes for enhanced transdermal delivery

GF Balata, MM Faisal, HA Elghamry… - Journal of drug delivery …, 2020 - Elsevier
Ivabradine HCl (IVB) is used in treatment of stable angina pectoris. The aim of the work was
to prepare a once daily transdermal film of transfersomes loaded IVB. Transfersomes were …

Hydrogel-forming microneedle arrays exhibit antimicrobial properties: Potential for enhanced patient safety

RF Donnelly, TRR Singh, AZ Alkilani… - International journal of …, 2013 - Elsevier
We describe, for the first time, the microbial characterisation of hydrogel-forming polymeric
microneedle arrays and the potential for passage of microorganisms into skin following …

[HTML][HTML] Tip loaded cyclodextrin-carvedilol complexes microarray patches

QK Anjani, AHB Sabri, KA Hamid… - Carbohydrate …, 2023 - Elsevier
Carvedilol, a β-blocker prescribed for chronic heart failure, suffers from poor bioavailability
and rapid first pass metabolism when administered orally. Herein, we present the …

[PDF][PDF] Transdermal drug delivery systems: approaches and advancements in drug absorption through skin

VC Jhawat, V Saini, S Kamboj… - Int J Pharm Sci Rev …, 2013 - researchgate.net
Transdermal drug delivery is the application of drug on the skin surface so that it can
permeate through the skin and reaches the systemic circulation. Skin contains 10-70 hair …

Formulation and optimization of lacidipine loaded niosomal gel for transdermal delivery: in-vitro characterization and in-vivo activity

M Qumbar, SS Imam, J Ali, J Ahmad, A Ali - Biomedicine & …, 2017 - Elsevier
The aim of the present research work is to formulate lacidipine (LAC) loaded niosomes
formulation for the management of hypertension by thin film hydration technique. The …

Optimized nanoemulsifying systems with enhanced bioavailability of carvedilol

B Singh, R Singh, S Bandyopadhyay, R Kapil… - Colloids and Surfaces B …, 2013 - Elsevier
The current studies entail a novel approach of formulating the solid self-nanoemulsifying
drug delivery systems (S-SNEDDS) of carvedilol solely using rational blends of lipidic and …