Nonalcoholic fatty liver disease (NAFLD) is estimated to afflict approximately 1 billion
individuals worldwide. In a subset of NAFLD patients, who have the progressive form of …

Magnetic resonance elastography (MRE) is a versatile imaging technique for map** the
viscoelastic properties of soft biological tissues. It has been widely used to detect liver …

Bile acids activate farnesoid X receptor (FXR) and G protein–coupled bile acid receptor‐1
(aka Takeda G protein–coupled receptor‐5 [TGR5]) to regulate bile acid metabolism and …

Mechanical hallmarks of fibrotic microenvironments are both outcomes and causes of
fibrosis progression. Understanding how cells sense and transmit mechanical cues in the …

Chronic liver diseases often result in the development of liver fibrosis and ultimately,
cirrhosis. Treatment strategies and prognosis differ greatly depending on the severity of liver …

Background: Currently the treatment of non-alcoholic fatty liver disease (NAFLD) is based on
weight loss through lifestyle changes, such as exercise combined with calorie-restricted …

Non-invasive evaluation of liver fibrosis has evolved over the last couple of decades.
Currently, elastography techniques are the most widely used non-invasive methods for …

The first clinical application of magnetic resonance elastography (MRE) was in the
evaluation of chronic liver disease (CLD) for detection and staging of liver fibrosis. In the …

Background Little is known about the benefits of the use of dispersion slope (DS) as a
viscosity-related parameter derived from two-dimensional (2D) shear-wave elastography …