Mpox (formerly monkeypox): pathogenesis, prevention, and treatment

J Lu, H **ng, C Wang, M Tang, C Wu, F Ye… - … and Targeted Therapy, 2023 - nature.com
In 2022, a global outbreak of Mpox (formerly monkeypox) occurred in various countries
across Europe and America and rapidly spread to more than 100 countries and regions. The …

Mpox treatment evolution: past milestones, present advances, and future directions

A Ganesan, T Arunagiri, S Mani, VR Kumaran… - Naunyn-Schmiedeberg's …, 2024 - Springer
An underestimated worldwide health concern, Monkeypox (Mpox) is becoming a bigger
menace to the world's population. After smallpox was eradicated in 1970, Mpox was found in …

[HTML][HTML] Structure-based discovery of F. religiosa phytochemicals as potential inhibitors against Monkeypox (mpox) viral protein

RK Mohapatra, A Mahal, PK Mohapatra… - Journal of Biosafety and …, 2024 - Elsevier
Outbreaks of Monkeypox (mpox) in over 100 non-endemic countries in 2022 represented a
serious global health concern. Once a neglected disease, mpox has become a global public …

Pharmacological treatment and vaccines in monkeypox virus: a narrative review and bibliometric analysis

MA Shamim, P Satapathy, BK Padhi… - Frontiers in …, 2023 - frontiersin.org
Mpox (earlier known as monkeypox) virus infection is a recognized public health
emergency. There has been little research on the treatment options. This article reviews the …

Genistein is effective in inhibiting Orf virus infection in vitro by targeting viral RNA polymerase subunit RPO30 protein

P Lv, Z Fang, J Guan, L Lv, M Xu, X Liu, Z Li… - Frontiers in …, 2024 - frontiersin.org
Orf virus (ORFV), a typical member of the genus Parapoxvirus, Poxvirus family, causes a
contagious pustular dermatitis in sheep, goats, and humans. Poxviruses encode a …

Inhibition potential of natural flavonoids against selected omicron (B. 1.19) mutations in the spike receptor binding domain of SARS-CoV-2: A molecular modeling …

A Kumar, M Dutt, B Dehury… - Journal of …, 2025 - Taylor & Francis
Abstract The omicron (B. 1.19) variant of contagious severe acute respiratory syndrome
coronavirus 2 (SARS-CoV-2), is considered a variant of concern (VOC) due to its increased …

Exploration of drug repurposing for Mpox outbreaks targeting gene signatures and host-pathogen interactions

S Imani, S Aminnezhad, M Alikarami, Z Abedi… - Scientific Reports, 2024 - nature.com
Monkeypox (Mpox) is a growing public health concern, with complex interactions within host
systems contributing to its impact. This study employs multi-omics approaches to uncover …

Epidemiology, clinical characteristics, and transmission patterns of a novel Mpox (Monkeypox) outbreak in eastern Democratic Republic of the Congo (DRC): an …

LM Masirika, JC Udahemuka, P Ndishimye… - medRxiv, 2024 - medrxiv.org
Summary (abstract) Background In August 2023, an outbreak of mpox was reported in the
eastern part, South Kivu Province, of Democratic Republic of the Congo. In this study, we …

Therapeutic potential of Curcuma longa against monkeypox: antioxidant, anti-inflammatory, and computational insights

F Boudou, A Belakredar, A Keziz, L Aissani… - Frontiers in …, 2025 - frontiersin.org
Background Monkeypox (Mpox) is a re-emerging zoonotic disease with limited therapeutic
options, necessitating the exploration of novel antiviral agents. Curcuma longa (turmeric) is …

[HTML][HTML] Re-visiting mpox: Stealth Assault on the Brain and Emerging Biomedical Research Insights

A Thakur - Brain Disorders, 2024 - Elsevier
The recent global outbreak of mpox virus (MPXV) infections has reignited interest in this
zoonotic disease, mpox. As of August 2024, mpox continues to pose significant global health …