Caenorhabditis elegans is an important model organism with many useful features,
including rapid development and aging, easy cultivation, and genetic tractability. Survival …

The spatio-temporal regulation of gene expression determines the fate and function of
various cells and tissues and, as a consequence, the correct development and functioning of …

The Notch signalling pathway mediates cell fate decisions, and is tumour suppressive or
oncogenic depending on the context,. During lung development, Notch pathway activation …

Online application for survival analysis (OASIS) has served as a popular and convenient
platform for the statistical analysis of various survival data, particularly in the field of aging …

Cancer patient classification using predictive biomarkers for anti-cancer drug responses is
essential for improving therapeutic outcomes. However, current machine-learning-based …

Ageing is driven by a loss of cellular integrity. Given the major role of ubiquitin modifications
in cell function, here we assess the link between ubiquitination and ageing by quantifying …

Summary Reduced insulin/IGF-1-like signaling (IIS) extends C. elegans lifespan by
upregulating stress response (class I) and downregulating other (class II) genes through a …

Educators show great interest in participating in social-media communities, such as Twitter,
to support their professional development and learning. The majority of the research into …

Ageing is marked by physical decline. Caenorhabditis elegans is a valuable model for
identifying genetic regulatory mechanisms of ageing and longevity. Here we report a simple …

Transposable elements (TEs) are mobile genetic elements, highly enriched in
heterochromatin, that constitute a large percentage of the DNA content of eukaryotic …