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Polygenic adaptation: a unifying framework to understand positive selection
Most adaption processes have a polygenic genetic basis, but even with the recent explosive
growth of genomic data we are still lacking a unified framework describing the dynamics of …
growth of genomic data we are still lacking a unified framework describing the dynamics of …
Epistasis and adaptation on fitness landscapes
C Bank - Annual Review of Ecology, Evolution, and Systematics, 2022 - annualreviews.org
Epistasis occurs when the effect of a mutation depends on its carrier's genetic background.
Despite increasing evidence that epistasis for fitness is common, its role during evolution is …
Despite increasing evidence that epistasis for fitness is common, its role during evolution is …
[HTML][HTML] Reprint of the new paradigm of economic complexity
Economic complexity offers a potentially powerful paradigm to understand key societal
issues and challenges of our time. The underlying idea is that growth, development …
issues and challenges of our time. The underlying idea is that growth, development …
Digital technologies, innovation, and skills: Emerging trajectories and challenges
In order to better understand the complex and dialectical relationships between digital
technologies, innovation, and skills, it is necessary to improve our understanding of the …
technologies, innovation, and skills, it is necessary to improve our understanding of the …
The Open Innovation in Science research field: a collaborative conceptualisation approach
Openness and collaboration in scientific research are attracting increasing attention from
scholars and practitioners alike. However, a common understanding of these phenomena is …
scholars and practitioners alike. However, a common understanding of these phenomena is …
Statistically learning the functional landscape of microbial communities
Microbial consortia exhibit complex functional properties in contexts ranging from soils to
bioreactors to human hosts. Understanding how community composition determines …
bioreactors to human hosts. Understanding how community composition determines …
Supply network disruption and resilience: A network structural perspective
Increasingly, scholars recognize the importance of understanding supply network
disruptions. However, the literature still lacks a clear conceptualization of a network-level …
disruptions. However, the literature still lacks a clear conceptualization of a network-level …
A rugged yet easily navigable fitness landscape
Fitness landscape theory predicts that rugged landscapes with multiple peaks impair
Darwinian evolution, but experimental evidence is limited. In this study, we used genome …
Darwinian evolution, but experimental evidence is limited. In this study, we used genome …
Evolutionary pathways and trajectories in antibiotic resistance
Evolution is the hallmark of life. Descriptions of the evolution of microorganisms have
provided a wealth of information, but knowledge regarding “what happened” has precluded …
provided a wealth of information, but knowledge regarding “what happened” has precluded …
Empirical fitness landscapes and the predictability of evolution
The genotype–fitness map (that is, the fitness landscape) is a key determinant of evolution,
yet it has mostly been used as a superficial metaphor because we know little about its …
yet it has mostly been used as a superficial metaphor because we know little about its …