Personalized management of pheochromocytoma and paraganglioma

S Nölting, N Bechmann, D Taieb… - Endocrine …, 2022 - academic.oup.com
Pheochromocytomas/paragangliomas are characterized by a unique molecular landscape
that allows their assignment to clusters based on underlying genetic alterations. With around …

Pheochromocytoma and paraganglioma

HPH Neumann, WF Young Jr… - New England journal of …, 2019 - Mass Medical Soc
Pheochromocytoma and Paraganglioma Pheochromocytoma and paraganglioma are
related tumors that differ mainly in location; pheochromocytomas are adrenal, and …

[HTML][HTML] New developments in existing WHO entities and evolving molecular concepts: The Genitourinary Pathology Society (GUPS) update on renal neoplasia

K Trpkov, O Hes, SR Williamson, AJ Adeniran… - Modern Pathology, 2021 - Elsevier
Abstract The Genitourinary Pathology Society (GUPS) reviewed recent advances in renal
neoplasia, particularly post-2016 World Health Organization (WHO) classification, to provide …

Report from the international society of urological pathology (ISUP) consultation conference on molecular pathology of urogenital cancers: III: molecular pathology of …

SR Williamson, AJ Gill, P Argani, YB Chen… - The American journal …, 2020 - journals.lww.com
Renal cell carcinoma (RCC) subtypes are increasingly being discerned via their molecular
underpinnings. Frequently this can be correlated to histologic and immunohistochemical …

Overview of the 2022 WHO classification of familial endocrine tumor syndromes

V Nosé, A Gill, JMC Teijeiro, A Perren, L Erickson - Endocrine pathology, 2022 - Springer
This review of the familial tumor syndromes involving the endocrine organs is focused on
discussing the main updates on the upcoming fifth edition of the WHO Classification of …

Management of phaeochromocytoma and paraganglioma in patients with germline SDHB pathogenic variants: an international expert Consensus statement

D Taïeb, S Nölting, ND Perrier, M Fassnacht… - Nature Reviews …, 2024 - nature.com
Adult and paediatric patients with pathogenic variants in the gene encoding succinate
dehydrogenase (SDH) subunit B (SDHB) often have locally aggressive, recurrent or …

A review of the tumour spectrum of germline succinate dehydrogenase gene mutations: Beyond phaeochromocytoma and paraganglioma

J MacFarlane, KC Seong, C Bisambar… - Clinical …, 2020 - Wiley Online Library
The citric acid cycle, also known as the Krebs cycle, plays an integral role in cellular
metabolism and aerobic respiration. Mutations in genes encoding the citric acid cycle …

[HTML][HTML] Pheochromocytoma/paraganglioma: recent updates in genetics, biochemistry, immunohistochemistry, metabolomics, imaging and therapeutic options

K Antonio, MMN Valdez, L Mercado-Asis, D Taïeb… - Gland …, 2020 - ncbi.nlm.nih.gov
Pheochromocytomas and paragangliomas (PPGLs), rare chromaffin/neural crest cell tumors,
are commonly benign in their clinical presentation. However, there are a number of cases …

[HTML][HTML] Expanding the clinicopathological spectrum of succinate dehydrogenase-deficient renal cell carcinoma with a focus on variant morphologies: a study of 62 …

TL Fuchs, F Maclean, J Turchini, AC Vargas… - Modern Pathology, 2022 - Elsevier
Most succinate dehydrogenase (SDH)-deficient renal cell carcinomas (RCCs) demonstrate
stereotypical morphology characterized by bland eosinophilic cells with frequent …

Succinate dehydrogenase and MYC-associated factor X mutations in pituitary neuroendocrine tumours

PB Loughrey, F Roncaroli, E Healy… - Endocrine-related …, 2022 - erc.bioscientifica.com
Pituitary neuroendocrine tumours (PitNETs) associated with paragangliomas or
phaeochromocytomas are rare. SDHx variants are estimated to be associated with 0.3–1.8 …