Regulation of sterol synthesis in eukaryotes
Cholesterol is an essential component of mammalian cell membranes and is required for
proper membrane permeability, fluidity, organelle identity, and protein function. Cells …
proper membrane permeability, fluidity, organelle identity, and protein function. Cells …
Evolutionary conservation and adaptation in the mechanism that regulates SREBP action: what a long, strange tRIP it's been
Sterol regulatory element-binding proteins (SREBPs) are a subfamily of basic helix–loop–
helix leucine zipper (bHLH-LZ) transcription factors that are conserved from fungi to humans …
helix leucine zipper (bHLH-LZ) transcription factors that are conserved from fungi to humans …
Lost world of complex life and the late rise of the eukaryotic crown
Eukaryotic life appears to have flourished surprisingly late in the history of our planet. This
view is based on the low diversity of diagnostic eukaryotic fossils in marine sediments of mid …
view is based on the low diversity of diagnostic eukaryotic fossils in marine sediments of mid …
A Sterol-Regulatory Element Binding Protein Is Required for Cell Polarity, Hypoxia Adaptation, Azole Drug Resistance, and Virulence in Aspergillus fumigatus
SD Willger, S Puttikamonkul, KH Kim, JB Burritt… - PLoS …, 2008 - journals.plos.org
At the site of microbial infections, the significant influx of immune effector cells and the
necrosis of tissue by the invading pathogen generate hypoxic microenvironments in which …
necrosis of tissue by the invading pathogen generate hypoxic microenvironments in which …
Signaling from the Endoplasmic Reticulum Activates Brassinosteroid Signaling and Promotes Acclimation to Stress in Arabidopsis
The ability to acclimate to stresses enables plants to grow and develop under adverse
environmental conditions. Regulated intramembrane proteolysis (RIP) triggered by …
environmental conditions. Regulated intramembrane proteolysis (RIP) triggered by …
Functional interactions between sphingolipids and sterols in biological membranes regulating cell physiology
Sterols and sphingolipids are limited to eukaryotic cells, and their interaction has been
proposed to favor formation of lipid microdomains. Although there is abundant biophysical …
proposed to favor formation of lipid microdomains. Although there is abundant biophysical …
Outline of the biosynthesis and regulation of ergosterol in yeast
JF Liu, JJ **a, KL Nie, F Wang, L Deng - World Journal of Microbiology …, 2019 - Springer
Sterols are crucial functional components for eukaryotic cell membrane. Due to versatile
activities, sterols show wide applications in food and pharmaceutical industries. Ergosterol …
activities, sterols show wide applications in food and pharmaceutical industries. Ergosterol …
Sterol regulators of cholesterol homeostasis and beyond: the oxysterol hypothesis revisited and revised
This review traces the evolution of the 'Oxysterol Hypothesis', which was first formulated by
Kandutsch and colleagues in 1978. The original hypothesis asserted that the suppressive …
Kandutsch and colleagues in 1978. The original hypothesis asserted that the suppressive …
SREBP Coordinates Iron and Ergosterol Homeostasis to Mediate Triazole Drug and Hypoxia Responses in the Human Fungal Pathogen Aspergillus fumigatus
Sterol regulatory element binding proteins (SREBPs) are a class of basic helix-loop-helix
transcription factors that regulate diverse cellular responses in eukaryotes. Adding to the …
transcription factors that regulate diverse cellular responses in eukaryotes. Adding to the …
Regulation of Sterol Biosynthesis in the Human Fungal Pathogen Aspergillus fumigatus: Opportunities for Therapeutic Development
Sterols are a major component of eukaryotic cell membranes. For human fungal infections
caused by the filamentous fungus Aspergillus fumigatus, antifungal drugs that target sterol …
caused by the filamentous fungus Aspergillus fumigatus, antifungal drugs that target sterol …