Peptides are fragments of proteins that carry out biological functions. They act as signaling
entities via all domains of life and interfere with protein-protein interactions, which are …

Intracellular delivery is a key step in biological research and has enabled decades of
biomedical discoveries. It is also becoming increasingly important in industrial and medical …

As the mainstay in the treatment of various cancers, chemotherapy plays a vital role, but still
faces many challenges, such as poor tumour selectivity and multidrug resistance (MDR) …

The lack of safe and efficient gene-delivery methods is a limiting obstacle to human gene
therapy. Synthetic gene-delivery agents, although safer than recombinant viruses, generally …

Despite continuous improvements in delivery systems, the development of methods for
efficient and specific delivery of targeted therapeutic agents still remains an issue in …

Nanotechnology has been widely used in the development of new strategies for drug
delivery and cancer therapy. Compared to traditional drug delivery systems, nano-based …

Ionizable lipid nanoparticles (LNPs) are the most clinically advanced nano‐delivery system
for therapeutic nucleic acids. The great effort put in the development of ionizable lipids with …

While the peptide and protein therapeutic market has developed significantly in the past
decades, delivery has limited their use. Although oral delivery is preferred, most are …

Endocytosis is a fundamental process in which eukaryotic cells internalise molecules and
macromolecules via deformation of the membrane and generation of membrane-bound …

Since the elucidation of the molecular structure of nucleic acids and understanding of their
role in encoding and translating genetic information into biological function, 1 the knowledge …