The predominantly animal-centric approach of chemical safety assessment has increasingly
come under pressure. Society is questioning overall performance, sustainability, continued …

Graphene and its derivatives are heralded as “miracle” materials with manifold applications
in different sectors of society from electronics to energy storage to medicine. The increasing …

Interest in the presence and effects of diclofenac (DCF) and other pharmaceutical products
(PPs) in the aquatic environment has been growing over the last 20 years. DCF has been …

Pesticides inevitably enter aquatic environments, posing potential risks to organisms. The
common aquatic model organism, zebrafish (Danio rerio), are widely used to evaluate the …

In silico toxicology is an emerging field. It gains increasing importance as research is aiming
to decrease the use of animal experiments as suggested in the 3R principles by Russell and …

Because it is only possible to test chemicals for effects on a restricted range of species and
exposure scenarios, ecotoxicologists are faced with a significant challenge of how to …

Toxicity testing and regulation of advanced materials at the nanoscale, ie nanosafety, is
challenged by the growing number of nanomaterials and their property variants requiring …

Metabolomics is a widely used technology in academic research, yet its application to
regulatory science has been limited. The most commonly cited barrier to its translation is …

Aquatic invertebrates play a pivotal role in (eco) toxicological assessments because they
offer ethical, cost‐effective and repeatable testing options. Additionally, their significance in …

Volatile organic compounds (VOCs) are widespread harmful atmospheric pollutants, which
have long been concerned and elucidated to be one of the risks of acute and chronic …