Cardiovascular disease in children with chronic kidney disease

MM Mitsnefes - Journal of the American Society of Nephrology, 2012 - journals.lww.com
More than a decade ago, cardiovascular disease (CVD) was recognized as a major cause of
death in children with advanced CKD. This observation has sparked the publication of …

Mineral bone disorders in chronic kidney disease

YC Hou, CL Lu, KC Lu - Nephrology, 2018 - Wiley Online Library
As the GFR loss aggravates, the disturbed mineral metabolism worsens the bone
microstructure and remodelling‐scenario, which is known as CKD‐mineral bone disease …

Vitamin D toxicity, policy, and science

R Vieth - Journal of Bone and Mineral Research, 2007 - academic.oup.com
Abstract The serum 25‐hydroxyvitamin D [25 (OH) D] concentration that is the threshold for
vitamin D toxicity has not been established. Hypercalcemia is the hazard criterion for vitamin …

Vitamin D and vascular calcification

A Zittermann, SS Schleithoff… - Current opinion in …, 2007 - journals.lww.com
Vitamin D and vascular calcification : Current Opinion in Lipidology Vitamin D and vascular
calcification : Current Opinion in Lipidology Log in or Register Subscribe to journalSubscribe Get …

Extrarenal Vitamin D Activation and Interactions Between Vitamin D2, Vitamin D3, and Vitamin D Analogs

G Jones - Annual review of nutrition, 2013 - annualreviews.org
Our understanding of the mechanism of action of vitamin D has been broadened by the
discovery of the extrarenal 1α-hydroxylase (CYP27B1) in various vitamin D target tissues …

Cholecalciferol supplementation alters calcitriol-responsive monocyte proteins and decreases inflammatory cytokines in ESRD

JR Stubbs, A Idiculla, J Slusser, R Menard… - Journal of the …, 2010 - journals.lww.com
In vitro, monocyte 1α-hydroxylase converts 25-hydroxyvitamin D [25 (OH) D] to 1, 25-
dihydroxyvitamin D to regulate local innate immune responses, but whether 25 (OH) D …

Mineral metabolism and vascular damage in children on dialysis

RC Shroff, AE Donald, MP Hiorns… - Journal of the …, 2007 - journals.lww.com
Cardiovascular disease is increasingly recognized as a life-limiting problem in young
patients with chronic kidney disease, but there are few studies in children that describe its …

[HTML][HTML] The dualistic role of vitamin D in vascular calcifications

MS Razzaque - Kidney international, 2011 - Elsevier
Vitamin D is a multifunctional hormone that can affect many essential biological functions,
ranging from the immune regulation to mineral ion metabolism. A close association between …

Cardiovascular complications of pediatric chronic kidney disease

MM Mitsnefes - Pediatric Nephrology, 2008 - Springer
Cardiovascular disease (CVD) mortality is a leading cause of death in adult chronic kidney
disease (CKD), with exceptionally high rates in young adults, according to the Task Force on …

Vitamin D treatment attenuates cardiac FGF23/FGFR4 signaling and hypertrophy in uremic rats

M Leifheit-Nestler, A Grabner… - Nephrology Dialysis …, 2017 - academic.oup.com
Background. Vitamin D deficiency and excess of circulating fibroblast growth factor 23
(FGF23) contribute to cardiovascular mortality in patients with chronic kidney disease (CKD) …