Oxidative stress and antioxidants in age-related macular degeneration

N Kushwah, K Bora, M Maurya, MC Pavlovich, J Chen - Antioxidants, 2023 - mdpi.com
Oxidative stress plays a crucial role in aging-related eye diseases, including age-related
macular degeneration (AMD), cataracts, and glaucoma. With age, antioxidant reparative …

Oxidative stress-induced cellular senescence in aging retina and age-related macular degeneration

R Terao, T Ahmed, A Suzumura, H Terasaki - Antioxidants, 2022 - mdpi.com
Aging leads to a gradual decline of function in multiple organs. Cataract, glaucoma, diabetic
retinopathy, and age-related macular degeneration (AMD) are age-related ocular diseases …

The potential for mitochondrial therapeutics in the treatment of primary open-angle glaucoma: a review

G Kuang, M Halimitabrizi, AA Edziah, R Salowe… - Frontiers in …, 2023 - frontiersin.org
Glaucoma, an age-related neurodegenerative disease, is characterized by the death of
retinal ganglion cells (RGCs) and the corresponding loss of visual fields. This disease is the …

Cytoprotective activities of representative nutrients from the Mediterranean diet and of Mediterranean oils against 7-ketocholesterol-and 7β-hydroxycholesterol …

L Rezig, I Ghzaiel, M Ksila, A Yammine, T Nury… - Steroids, 2022 - Elsevier
ketocholesterol and 7β-hydroxycholesterol are two oxysterols mainly formed by the
autoxidation of cholesterol. These two molecules are interconvertible via specific enzymes …

The role of oxidative stress in the aging eye

D Goodman, S Ness - Life, 2023 - mdpi.com
Given the expanding elderly population in the United States and the world, it is important to
understand the processes underlying both natural and pathological age-related changes in …

Phytochemical and safety evaluations of finger lime, mountain pepper, and tamarind in zebrafish embryos

PR Cáceres-Vélez, A Ali, A Fournier-Level… - Antioxidants, 2022 - mdpi.com
Plants play a pivotal role in drug discovery, constituting 50% of modern pharmacopeia.
Many human diseases, including age-related degenerative diseases, converge onto …

[HTML][HTML] Stressed out-The role of oxidative stress in airway smooth muscle dysfunction in asthma and COPD

RM Saunders, M Biddle, Y Amrani… - Free Radical Biology and …, 2022 - Elsevier
The airway smooth muscle (ASM) surrounding the airways is dysfunctional in both asthma
and chronic obstructive pulmonary disease (COPD), exhibiting; increased contraction …

[HTML][HTML] Mitochondrial dysfunction in glaucomatous degeneration

ZQ Zhang, Z **e, SY Chen, X Zhang - International Journal of …, 2023 - ncbi.nlm.nih.gov
Glaucoma is a kind of optic neuropathy mainly manifested in the permanent death of retinal
ganglion cells (RGCs), atrophy of the optic nerve, and loss of visual ability. The main risk …

Glaucoma and dietary links: insights from high-salt intake, the Mediterranean diet, and specific nutrients

Y Yang, H Zhou, Z Hong - Frontiers in Nutrition, 2024 - frontiersin.org
Glaucoma, a prevalent and potentially blinding eye disease, is linked to a variety of factors,
including elevated intraocular pressure, optic nerve damage, and oxidative stress. In recent …

Development of mucoadhesive methacrylic anhydride-modified hydroxypropyl methylcellulose hydrogels for topical ocular drug delivery

YH Cheng, MP Fung, YQ Chen, YC Chiu - Journal of Drug Delivery Science …, 2024 - Elsevier
Oxidative stress is a key factor involved in the development and progression of glaucoma.
Curcumin is a natural phenolic compound with antioxidant and ant-inflammatory properties …