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Biomarkers for breast cancer immunotherapy: PD-L1, TILs, and beyond
A Rizzo, AD Ricci - Expert opinion on investigational drugs, 2022 - Taylor & Francis
ABSTRACT Introduction Immune checkpoint inhibitors (ICIs) have recently entered into the
therapeutic scenario of metastatic breast cancer. However, only a proportion of patients …
therapeutic scenario of metastatic breast cancer. However, only a proportion of patients …
Inhibition of ATM promotes PD-L1 expression by activating JNK/c-Jun/TNF-α signaling axis in triple-negative breast cancer
C Liu, X Qian, C Yu, X **a, J Li, Y Li, Y **e, G Gao… - Cancer Letters, 2024 - Elsevier
Triple-negative breast cancer (TNBC) is a heterogeneous subtype of breast cancer. Anti-PD-
1/PD-L1 treatment for advanced TNBC is still limited to PD-L1-positive patients. Ataxia …
1/PD-L1 treatment for advanced TNBC is still limited to PD-L1-positive patients. Ataxia …
Clinical impact of PD-L1 expression in triple-negative breast cancer patients with residual tumor burden after neoadjuvant chemotherapy
Abstract Background Studies on PD-L1 expression in breast cancer have gained importance
in recent years, especially in triple-negative breast cancer (TNBC). Our aim was to analyze …
in recent years, especially in triple-negative breast cancer (TNBC). Our aim was to analyze …
Experimental and clinical evidence in favour of an effective immune stimulation in ER-positive, endocrine-dependent metastatic breast cancer
In ER+ breast cancer, usually seen as the low immunogenic type, the main mechanisms
favouring the immune response or tumour growth and immune evasion in the tumour …
favouring the immune response or tumour growth and immune evasion in the tumour …
Convolutional neural network for biomarker discovery for triple negative breast cancer with RNA sequencing data
Triple negative breast cancers (TNBCs) are tumors with a poor treatment response and
prognosis. In this study, we propose a new approach, candidate extraction from …
prognosis. In this study, we propose a new approach, candidate extraction from …
[HTML][HTML] Combined positive score for programmed death ligand-1 expression and inflammatory microenvironment in gastrointestinal stromal tumors
Background and Objectives: GISTs are the most frequent type of mesenchymal neoplasm of
the digestive tract. The prognosis is mainly determined by tumor dimensions, mitotic rate and …
the digestive tract. The prognosis is mainly determined by tumor dimensions, mitotic rate and …
[HTML][HTML] 肿瘤间质浸润淋巴细胞与乳腺癌新辅助化疗效果的相关性
姬文莉， 陈海霞， 王翠翠， 刘艳梅， 岳娜… - Advances in Clinical …, 2023 - hanspub.org
目的: 评估乳腺癌穿刺标本中肿瘤间质浸润淋巴细胞(stromal tumor-infiltrating lymphocytes,
sTILs) 与新辅助化疗效果的相关性. 方法: 收集126 例乳腺癌穿刺标本及其新辅助化疗后手术 …
sTILs) 与新辅助化疗效果的相关性. 方法: 收集126 例乳腺癌穿刺标本及其新辅助化疗后手术 …
Prognostische Relevanz der PD-L1 Expression beim Mammakarzinom
CP Marcus - 2020 - ediss.sub.uni-hamburg.de
Therapien mit Immun-Checkpoint-Inhibitoren sind aus der modernen Onkologie nicht mehr
wegzudenken. Zahlreiche Medikamente inhibieren PD1 oder PD-L1, ein Regelsystem …
wegzudenken. Zahlreiche Medikamente inhibieren PD1 oder PD-L1, ein Regelsystem …