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Virulence Factors of Pseudomonas Aeruginosa and Antivirulence Strategies to Combat Its Drug Resistance
C Liao, X Huang, Q Wang, D Yao, W Lu - Frontiers in cellular and …, 2022 - frontiersin.org
Pseudomonas aeruginosa is an opportunistic pathogen causing nosocomial infections in
severely ill and immunocompromised patients. Ubiquitously disseminated in the …
severely ill and immunocompromised patients. Ubiquitously disseminated in the …
[HTML][HTML] It is the time for quorum sensing inhibition as alternative strategy of antimicrobial therapy
Multiple drug resistance poses a significant threat to public health worldwide, with a
substantial increase in morbidity and mortality rates. Consequently, searching for novel …
substantial increase in morbidity and mortality rates. Consequently, searching for novel …
Different drugs for bad bugs: antivirulence strategies in the age of antibiotic resistance
The rapid evolution and dissemination of antibiotic resistance among bacterial pathogens
are outpacing the development of new antibiotics, but antivirulence agents provide an …
are outpacing the development of new antibiotics, but antivirulence agents provide an …
The effects of antibiotics on the microbiome throughout development and alternative approaches for therapeutic modulation
The widespread use of antibiotics in the past 80 years has saved millions of human lives,
facilitated technological progress and killed incalculable numbers of microbes, both …
facilitated technological progress and killed incalculable numbers of microbes, both …
Quorum-sensing systems as targets for antivirulence therapy
T Defoirdt - Trends in microbiology, 2018 - cell.com
The development of novel therapies to control diseases caused by antibiotic-resistant
pathogens is one of the major challenges we are currently facing. Many important plant …
pathogens is one of the major challenges we are currently facing. Many important plant …
Recent advances in anti-virulence therapeutic strategies with a focus on dismantling bacterial membrane microdomains, toxin neutralization, quorum-sensing …
Antimicrobial resistance constitutes one of the major challenges facing humanity in the
Twenty-First century. The spread of resistant pathogens has been such that the possibility of …
Twenty-First century. The spread of resistant pathogens has been such that the possibility of …
Interference in bacterial quorum sensing: a biopharmaceutical perspective
Numerous bacteria utilize molecular communication systems referred to as quorum sensing
(QS) to synchronize the expression of certain genes regulating, among other aspects, the …
(QS) to synchronize the expression of certain genes regulating, among other aspects, the …
Quorum quenching: role in nature and applied developments
C Grandclément, M Tannières, S Moréra… - FEMS microbiology …, 2016 - academic.oup.com
Quorum sensing (QS) refers to the capacity of bacteria to monitor their population density
and regulate gene expression accordingly: the QS-regulated processes deal with …
and regulate gene expression accordingly: the QS-regulated processes deal with …
Quorum sensing inhibitors as antipathogens: biotechnological applications
The mechanisms through which microbes communicate using signal molecules has inspired
a great deal of research. Microbes use this exchange of information, known as quorum …
a great deal of research. Microbes use this exchange of information, known as quorum …
Plant natural products targeting bacterial virulence factors
Decreased antimicrobial efficiency has become a global public health issue. The paucity of
new antibacterial drugs is evident, and the arsenal against infectious diseases needs to be …
new antibacterial drugs is evident, and the arsenal against infectious diseases needs to be …