Helminths have evolved to become experts at subverting immune surveillance. Through
potent and persistent immune tempering, helminths can remain undetected in human …

Helminths are masterful immunoregulators. A characteristic feature of helminth infection is a
Th2-dominated immune response, but stimulation of immunoregulatory cell populations …

Galectins, which were first characterized in the mid-1970s, were assigned a role in the
recognition of endogenous ('self') carbohydrate ligands in embryogenesis, development and …

Schistosomiasis is a neglected tropical disease caused by blood flukes (genus
Schistosoma; schistosomes) and affecting 200 million people worldwide. No vaccines are …

Parasitic diseases have a devastating, long-term impact on human health, welfare and food
production worldwide. More than two billion people are infected with geohelminths …

Parasitic helminths release molecules into their environment, which are generally referred to
as excretory-secretory products or ES. ES derived from a wide range of nematodes …

To infect their mammalian hosts, Fasciola hepatica larvae must penetrate and traverse the
intestinal wall of the duodenum, move through the peritoneum, and penetrate the liver. After …

Background The barber's pole worm, Haemonchus contortus, is one of the most
economically important parasites of small ruminants worldwide. Although this parasite can …

Lymphatic filariasis (LF) is a socio-economically devastating mosquito-borne Neglected
Tropical Disease caused by parasitic filarial nematodes. The interaction between the …

The root knot nematode, Meloidogyne incognita, is an obligate parasite that causes
significant damage to a broad range of host plants. Infection is associated with secretion of …