Towards more tolerable subcutaneous administration: review of contributing factors for improving combination product design

N Mathias, S Huille, M Picci, RP Mahoney… - Advanced Drug Delivery …, 2024 - Elsevier
Subcutaneous (SC) injections can be associated with local pain and discomfort that is
subjective and may affect treatment adherence and overall patient experience. With …

The mechanisms and management of persistent postsurgical pain

AM Fuller, S Bharde, S Sikandar - Frontiers in Pain Research, 2023 - frontiersin.org
An estimated 10%–50% of patients undergoing a surgical intervention will develop
persistent postsurgical pain (PPP) lasting more than 3 months despite adequate acute pain …

[HTML][HTML] Effectiveness of dexmedetomidine on patient-centred outcomes in surgical patients: a systematic review and Bayesian meta-analysis

M Verret, JBP Le, MM Lalu, MS Jeffers… - British journal of …, 2024 - Elsevier
Background Dexmedetomidine is increasingly used for surgical patients requiring general
anaesthesia. However, its effectiveness on patient-centred outcomes remains uncertain. Our …

Peri‐operative pain management in adults: a multidisciplinary consensus statement from the Association of Anaesthetists and the British Pain Society

K El‐Boghdadly, NA Levy, WJ Fawcett… - …, 2024 - Wiley Online Library
Background Nearly half of adult patients undergoing surgery experience moderate or severe
postoperative pain. Inadequate pain management hampers postoperative recovery and …

[HTML][HTML] No place for routine use of modified-release opioids in postoperative pain management

J Quinlan, N Levy, DN Lobo, PE Macintyre - British Journal of Anaesthesia, 2022 - Elsevier
Modified-release opioid tablets were introduced into surgical practice in the belief that they
provided superior pain relief and reduced nursing workload, and they rapidly became …

[HTML][HTML] Beyond measurement: a deep dive into the commonly used pain scales for postoperative pain assessment

S Choi, SH Yoon, HJ Lee - The Korean Journal of Pain, 2024 - synapse.koreamed.org
This review explores the essential methodologies for effective postoperative pain
management, focusing on the need for thorough pain assessment tools, as underscored in …

[HTML][HTML] The psychometric assessment of the older adult in pain: A systematic review of assessment instruments

AIG McLennan, EM Winters, MM Gagnon… - Clinical Psychology …, 2024 - Elsevier
We conducted a systematic review of pain assessment tools suitable for community-dwelling
older adults. For this work, we conceptualized existing psychometric tools as falling under …

Methodological quality of 100 recent systematic reviews of health-related outcome measurement instruments: an overview of reviews

EBM Elsman, LB Mokkink, IL Abma, OL Aiyegbusi… - Quality of Life …, 2024 - Springer
Purpose Systematic reviews evaluating and comparing the measurement properties of
outcome measurement instruments (OMIs) play an important role in OMI selection. Earlier …

[HTML][HTML] To Be in Pain: Pain Multidimensional Questionnaire as Reliable Tool to Evaluate Multifaceted Aspects of Pain

G Forte, F Favieri, V De Pascalis… - Journal of Clinical …, 2024 - mdpi.com
Background/Objectives: Pain is a multidimensional experience influenced by sensory,
emotional, and cognitive factors. Traditional pain assessments often fail to capture this …

Enhanced recovery after surgery for craniotomies: a systematic review and meta-analysis

SH Kim, SH Choi, J Moon, HD Kim… - Journal of Neurosurgical …, 2025 - journals.lww.com
The efficacy of the enhanced recovery after surgery (ERAS) protocols in neurosurgery has
not yet been established. We performed a systematic review and meta-analysis of …