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Towards more tolerable subcutaneous administration: review of contributing factors for improving combination product design
N Mathias, S Huille, M Picci, RP Mahoney… - Advanced Drug Delivery …, 2024 - Elsevier
Subcutaneous (SC) injections can be associated with local pain and discomfort that is
subjective and may affect treatment adherence and overall patient experience. With …
subjective and may affect treatment adherence and overall patient experience. With …
The mechanisms and management of persistent postsurgical pain
AM Fuller, S Bharde, S Sikandar - Frontiers in Pain Research, 2023 - frontiersin.org
An estimated 10%–50% of patients undergoing a surgical intervention will develop
persistent postsurgical pain (PPP) lasting more than 3 months despite adequate acute pain …
persistent postsurgical pain (PPP) lasting more than 3 months despite adequate acute pain …
[HTML][HTML] Effectiveness of dexmedetomidine on patient-centred outcomes in surgical patients: a systematic review and Bayesian meta-analysis
Background Dexmedetomidine is increasingly used for surgical patients requiring general
anaesthesia. However, its effectiveness on patient-centred outcomes remains uncertain. Our …
anaesthesia. However, its effectiveness on patient-centred outcomes remains uncertain. Our …
Peri‐operative pain management in adults: a multidisciplinary consensus statement from the Association of Anaesthetists and the British Pain Society
Background Nearly half of adult patients undergoing surgery experience moderate or severe
postoperative pain. Inadequate pain management hampers postoperative recovery and …
postoperative pain. Inadequate pain management hampers postoperative recovery and …
[HTML][HTML] No place for routine use of modified-release opioids in postoperative pain management
Modified-release opioid tablets were introduced into surgical practice in the belief that they
provided superior pain relief and reduced nursing workload, and they rapidly became …
provided superior pain relief and reduced nursing workload, and they rapidly became …
[HTML][HTML] Beyond measurement: a deep dive into the commonly used pain scales for postoperative pain assessment
S Choi, SH Yoon, HJ Lee - The Korean Journal of Pain, 2024 - synapse.koreamed.org
This review explores the essential methodologies for effective postoperative pain
management, focusing on the need for thorough pain assessment tools, as underscored in …
management, focusing on the need for thorough pain assessment tools, as underscored in …
[HTML][HTML] The psychometric assessment of the older adult in pain: A systematic review of assessment instruments
We conducted a systematic review of pain assessment tools suitable for community-dwelling
older adults. For this work, we conceptualized existing psychometric tools as falling under …
older adults. For this work, we conceptualized existing psychometric tools as falling under …
Methodological quality of 100 recent systematic reviews of health-related outcome measurement instruments: an overview of reviews
Purpose Systematic reviews evaluating and comparing the measurement properties of
outcome measurement instruments (OMIs) play an important role in OMI selection. Earlier …
outcome measurement instruments (OMIs) play an important role in OMI selection. Earlier …
[HTML][HTML] To Be in Pain: Pain Multidimensional Questionnaire as Reliable Tool to Evaluate Multifaceted Aspects of Pain
Background/Objectives: Pain is a multidimensional experience influenced by sensory,
emotional, and cognitive factors. Traditional pain assessments often fail to capture this …
emotional, and cognitive factors. Traditional pain assessments often fail to capture this …
Enhanced recovery after surgery for craniotomies: a systematic review and meta-analysis
SH Kim, SH Choi, J Moon, HD Kim… - Journal of Neurosurgical …, 2025 - journals.lww.com
The efficacy of the enhanced recovery after surgery (ERAS) protocols in neurosurgery has
not yet been established. We performed a systematic review and meta-analysis of …
not yet been established. We performed a systematic review and meta-analysis of …