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Representation learning applications in biological sequence analysis
Although remarkable advances have been reported in high-throughput sequencing, the
ability to aptly analyze a substantial amount of rapidly generated biological …
ability to aptly analyze a substantial amount of rapidly generated biological …
Common methods for phylogenetic tree construction and their implementation in R
Y Zou, Z Zhang, Y Zeng, H Hu, Y Hao, S Huang, B Li - Bioengineering, 2024 - mdpi.com
A phylogenetic tree can reflect the evolutionary relationships between species or gene
families, and they play a critical role in modern biological research. In this review, we …
families, and they play a critical role in modern biological research. In this review, we …
GeoPhy: differentiable phylogenetic inference via geometric gradients of tree topologies
Phylogenetic inference, grounded in molecular evolution models, is essential for
understanding the evolutionary relationships in biological data. Accounting for the …
understanding the evolutionary relationships in biological data. Accounting for the …
A machine-learning-based alternative to phylogenetic bootstrap
Motivation Currently used methods for estimating branch support in phylogenetic analyses
often rely on the classic Felsenstein's bootstrap, parametric tests, or their approximations. As …
often rely on the classic Felsenstein's bootstrap, parametric tests, or their approximations. As …
[HTML][HTML] Learning hyperbolic embedding for phylogenetic tree placement and updates
Simple Summary We show how the conventional (Euclidean) deep learning methods
developed for phylogenetics can benefit from using hyperbolic geometry. The results point to …
developed for phylogenetics can benefit from using hyperbolic geometry. The results point to …
Hyperbolic optimizer as a dynamical system
During the last few years, the field of dynamical systems has been develo** innovative
tools to study the asymptotic behavior of different optimizers in the context of neural …
tools to study the asymptotic behavior of different optimizers in the context of neural …
Lea** through tree space: continuous phylogenetic inference for rooted and unrooted trees
Phylogenetics is now fundamental in life sciences, providing insights into the earliest
branches of life and the origins and spread of epidemics. However, finding suitable …
branches of life and the origins and spread of epidemics. However, finding suitable …
Fidelity of hyperbolic space for Bayesian phylogenetic inference
Bayesian inference for phylogenetics is a gold standard for computing distributions of
phylogenies. However, Bayesian phylogenetics faces the challenging computational …
phylogenies. However, Bayesian phylogenetics faces the challenging computational …
On procrustes analysis in hyperbolic space
Congruent Procrustes analysis aims to find the best matching between two point sets
through rotation, reflection and translation. We formulate the Procrustes problem for …
through rotation, reflection and translation. We formulate the Procrustes problem for …
Variational Bayesian phylogenies through matrix representation of tree space
RR Bouckaert - PeerJ, 2024 - peerj.com
In this article, we study the distance matrix as a representation of a phylogeny by way of
hierarchical clustering. By defining a multivariate normal distribution on (a subset of) the …
hierarchical clustering. By defining a multivariate normal distribution on (a subset of) the …