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Microglia in neurodegenerative diseases: mechanism and potential therapeutic targets
C Gao, J Jiang, Y Tan, S Chen - Signal transduction and targeted …, 2023 - nature.com
Microglia activation is observed in various neurodegenerative diseases. Recent advances in
single-cell technologies have revealed that these reactive microglia were with high spatial …
single-cell technologies have revealed that these reactive microglia were with high spatial …
[HTML][HTML] Neurocognitive, physiological, and biophysical effects of transcranial alternating current stimulation
Transcranial alternating current stimulation (tACS) can modulate human neural activity and
behavior. Accordingly, tACS has vast potential for cognitive research and brain disorder …
behavior. Accordingly, tACS has vast potential for cognitive research and brain disorder …
Multisensory gamma stimulation promotes glymphatic clearance of amyloid
The glymphatic movement of fluid through the brain removes metabolic waste,,–.
Noninvasive 40 Hz stimulation promotes 40 Hz neural activity in multiple brain regions and …
Noninvasive 40 Hz stimulation promotes 40 Hz neural activity in multiple brain regions and …
Neuronal dynamics direct cerebrospinal fluid perfusion and brain clearance
The accumulation of metabolic waste is a leading cause of numerous neurological
disorders, yet we still have only limited knowledge of how the brain performs self-cleansing …
disorders, yet we still have only limited knowledge of how the brain performs self-cleansing …
Forty-hertz light stimulation does not entrain native gamma oscillations in Alzheimer's disease model mice
There is a demand for noninvasive methods to ameliorate disease. We investigated whether
40-Hz flickering light entrains gamma oscillations and suppresses amyloid-β in the brains of …
40-Hz flickering light entrains gamma oscillations and suppresses amyloid-β in the brains of …
Precuneus magnetic stimulation for Alzheimer's disease: a randomized, sham-controlled trial
Repetitive transcranial magnetic stimulation (rTMS) is emerging as a non-invasive
therapeutic strategy in the battle against Alzheimer's disease. Alzheimer's disease patients …
therapeutic strategy in the battle against Alzheimer's disease. Alzheimer's disease patients …
Immune activation in Alzheimer disease
Alzheimer disease (AD) is the most common neurodegenerative disease, and with no
efficient curative treatment available, its medical, social, and economic burdens are …
efficient curative treatment available, its medical, social, and economic burdens are …
Challenges and hopes for Alzheimer's disease
SA Tatulian - Drug discovery today, 2022 - Elsevier
Recent drug development efforts targeting Alzheimer's disease (AD) have failed to produce
effective disease-modifying agents for many reasons, including the substantial …
effective disease-modifying agents for many reasons, including the substantial …
Large-scale deep multi-layer analysis of Alzheimer's disease brain reveals strong proteomic disease-related changes not observed at the RNA level
The biological processes that are disrupted in the Alzheimer's disease (AD) brain remain
incompletely understood. In this study, we analyzed the proteomes of more than 1,000 brain …
incompletely understood. In this study, we analyzed the proteomes of more than 1,000 brain …
[HTML][HTML] Gamma frequency sensory stimulation in mild probable Alzheimer's dementia patients: Results of feasibility and pilot studies
Non-invasive Gamma ENtrainment Using Sensory stimulation (GENUS) at 40Hz reduces
Alzheimer's disease (AD) pathology such as amyloid and tau levels, prevents cerebral …
Alzheimer's disease (AD) pathology such as amyloid and tau levels, prevents cerebral …