Pediatric dilated cardiomyopathy: a review of current clinical approaches and pathogenesis
I Malinow, DC Fong, M Miyamoto, S Badran… - Frontiers in …, 2024 - frontiersin.org
Pediatric dilated cardiomyopathy (DCM) is a rare, yet life-threatening cardiovascular
condition characterized by systolic dysfunction with biventricular dilatation and reduced …
condition characterized by systolic dysfunction with biventricular dilatation and reduced …
In Search of a Target Gene for a Desirable Phenotype in Aquaculture: Genome Editing of Cyprinidae and Salmonidae Species
SY Orlova, MN Ruzina, OR Emelianova, AA Sergeev… - Genes, 2024 - mdpi.com
Aquaculture supplies the world food market with a significant amount of valuable protein.
Highly productive aquaculture fishes can be derived by utilizing genome-editing methods …
Highly productive aquaculture fishes can be derived by utilizing genome-editing methods …
A Taybi-Linder syndrome-related RTTN variant impedes neural rosette formation in human cortical organoids
J Guguin, TY Chen, S Cuinat, A Besson… - PLoS …, 2024 - journals.plos.org
Taybi-Linder syndrome (TALS) is a rare autosomal recessive disorder characterized by
severe microcephaly with abnormal gyral pattern, severe growth retardation and bone …
severe microcephaly with abnormal gyral pattern, severe growth retardation and bone …
[HTML][HTML] Deciphering the genetic architecture of atrial fibrillation offers insights into disease prediction, pathophysiology and downstream sequelae
S Yuan, Y Li, L Wang, F Xu, J Chen, MG Levin, Y ** of transcriptomic signatures for cardiotoxic drugs
Drug-induced gene expression profiles can identify potential mechanisms of toxicity. We
focus on obtaining signatures for cardiotoxicity of FDA-approved tyrosine kinase inhibitors …
focus on obtaining signatures for cardiotoxicity of FDA-approved tyrosine kinase inhibitors …
A TALS-like RTTN mutation impedes neural rosette formation in human cortical organoids
Abstract The Taybi-Linder syndrome (TALS) is a rare genetic disorder characterized by a
severe microcephaly with abnormal gyral pattern, severe growth retardation, bone …
severe microcephaly with abnormal gyral pattern, severe growth retardation, bone …
[HTML][HTML] The PCM scaffold enables RNA localization to centrosomes
As microtubule-organizing centers, centrosomes direct assembly of the bipolar mitotic
spindle required for chromosome segregation and genome stability. Centrosome activity …
spindle required for chromosome segregation and genome stability. Centrosome activity …
A Specialized Centrosome-Proteasome Axis Mediates Proteostasis and Influences Cardiac Stress through Txlnb
Background Centrosomes localize to perinuclear foci where they serve multifunctional roles,
arranging the microtubule organizing center (MTOC) and anchoring ubiquitin-proteasome …
arranging the microtubule organizing center (MTOC) and anchoring ubiquitin-proteasome …