Liquid-metal-based three-dimensional microelectrode arrays integrated with implantable ultrathin retinal prosthesis for vision restoration
Electronic retinal prostheses for stimulating retinal neurons are promising for vision
restoration. However, the rigid electrodes of conventional retinal implants can inflict damage …
restoration. However, the rigid electrodes of conventional retinal implants can inflict damage …
Stimulation strategies for improving the resolution of retinal prostheses
Electrical stimulation using implantable devices with arrays of stimulating electrodes is an
emerging therapy for neurological diseases. The performance of these devices depends …
emerging therapy for neurological diseases. The performance of these devices depends …
A model of ganglion axon pathways accounts for percepts elicited by retinal implants
Degenerative retinal diseases such as retinitis pigmentosa and macular degeneration cause
irreversible vision loss in more than 10 million people worldwide. Retinal prostheses, now …
irreversible vision loss in more than 10 million people worldwide. Retinal prostheses, now …
Graphene-based microelectrodes with bidirectional functionality for next-generation retinal electronic interfaces
Neuroelectronic prostheses are being developed for restoring vision at the retinal level in
patients who have lost their sight due to photoreceptor loss. The core component of these …
patients who have lost their sight due to photoreceptor loss. The core component of these …
Spatially patterned bi-electrode epiretinal stimulation for axon avoidance at cellular resolution
Objective. Epiretinal prostheses are designed to restore vision to people blinded by
photoreceptor degenerative diseases by stimulating surviving retinal ganglion cells (RGCs) …
photoreceptor degenerative diseases by stimulating surviving retinal ganglion cells (RGCs) …
Avoidance of axonal stimulation with sinusoidal epiretinal stimulation
Objective. Neuromodulation, particularly electrical stimulation, necessitates high spatial
resolution to achieve artificial vision with high acuity. In epiretinal implants, this is hindered …
resolution to achieve artificial vision with high acuity. In epiretinal implants, this is hindered …
Discrimination of simple objects decoded from the output of retinal ganglion cells upon sinusoidal electrical stimulation
Objective. Most neuroprosthetic implants employ pulsatile square-wave electrical stimuli,
which are significantly different from physiological inter-neuronal communication. In case of …
which are significantly different from physiological inter-neuronal communication. In case of …
Capacitive-like photovoltaic epiretinal stimulation enhances and narrows the network-mediated activity of retinal ganglion cells by recruiting the lateral inhibitory …
Photovoltaic retinal prostheses theoretically offer the possibility of stand-alone high-
resolution electrical stimulation of the retina. However, achieving focused epiretinal …
resolution electrical stimulation of the retina. However, achieving focused epiretinal …
Global activity sha** strategies for a retinal implant
Objective. Retinal prostheses provide visual perception via electrical stimulation of the retina
using an implanted array of electrodes. The retinal activation resulting from each electrode is …
using an implanted array of electrodes. The retinal activation resulting from each electrode is …
Factors affecting two-point discrimination in Argus II patients
Two of the main obstacles to the development of epiretinal prosthesis technology are
electrodes that require current amplitudes above safety limits to reliably elicit percepts, and a …
electrodes that require current amplitudes above safety limits to reliably elicit percepts, and a …