Nitroxides, also known as nitroxyl radicals, are long-lived or stable radicals with the general
structure R1R2N–O•. The spin distribution over the nitroxide N and O atoms contributes to …

Transition-metal catalyzed C–H activation reactions have been proven to be useful
methodologies for the assembly of synthetically meaningful molecules. This approach bears …

Silver, known and utilized since ancient times, is a coinage metal, which has been widely
used for various organic transformations in the past few decades. Currently, the silver …

Direct olefinic C–H functionalization represents the ideal way of introducing an alkenyl
group into organic molecules. A well-known process is the Heck reaction, which involves …

Selective oxidation reactions are challenging when carried out on an industrial scale. Many
traditional methods are undesirable from an environmental or safety point of view. There is a …

The organic nitroxyl radical, TEMPO (2, 2, 6, 6-tetramethylpiperidine-N-oxyl), finds a variety
of industrial applications for chemical transformations. Because of economic and …

Compared with the popularity of various C-centred radicals, the N-centred radicals remain
largely unexplored in catalytic radical cascade reactions because of a lack of convenient …

A Ag-mediated C–H/P–H functionalization reaction of arylphosphine oxides with internal
alkynes was described for the direct preparation of benzo [b] phosphole oxides with a high …

It has been a long time since C–H bond oxidations first attracted chemists' attention. In the
last several decades, C–H bond oxidation has been extensively investigated and applied in …

The incorporation of a CF3 group in a compound of pharmacological relevance usually
results in significant enhancement of its lipophilicity, binding selectivity, and metabolic …