Vitamin D has a key role in stimulating calcium absorption from the gut and promoting
skeletal health, as well as many other important physiological functions. Vitamin D is …

This review focuses on the biologic importance of the vitamin D binding protein (DBP) with
emphasis on its regulation of total and free vitamin D metabolite levels in various clinical …

The global impact of childhood malnutrition is staggering. The synergism between
malnutrition and infection contributes substantially to childhood morbidity and mortality …

Background Randomised controlled trials (RCTs) of vitamin D to prevent COPD
exacerbations have yielded conflicting results. Individual participant data meta-analysis …

In the last 5 years, there has been a remarkable change in our understanding of the health
benefits of vitamin D. The classical actions of vitamin D as a determinant of mineral …

Control of tuberculosis worldwide depends on our understanding of human immune
mechanisms, which combat the infection. Acquired T cell responses are critical for host …

The vitamin D receptor (VDR) is a nuclear, ligand-dependent transcription factor that in
complex with hormonally active vitamin D, 1, 25 (OH) 2D3, regulates the expression of more …

Interaction between vitamin D and the immune system has been recognized for many years,
but its relevance to normal human physiology has only become evident in the past 5 years …

Calcidiol, the major circulating metabolite of vitamin D, supports induction of pleiotropic
antimicrobial responses in vitro. Vitamin D supplementation elevates circulating calcidiol …

Vitamin D metabolites enhance immunity to a wide range of respiratory pathogens in vitro.
Numerous observational studies have investigated whether vitamin D deficiency is a risk …