Hidden symmetry of the flavivirus protein shell and pH-controlled reconstruction of the viral surface

OV Konevtsova, IY Golushko, R Podgornik… - Biomaterials …, 2023 - pubs.rsc.org
Using recent Zika virus structural data we reveal a hidden symmetry of protein order in
immature and mature flavivirus shells, violating the Caspar–Klug paradigmatic model of …

Structural 3d domain reconstruction of the rna genome from viruses with secondary structure models

S Poblete, HV Guzman - Viruses, 2021 - mdpi.com
Three-dimensional RNA domain reconstruction is important for the assembly, disassembly
and delivery functionalities of a packed proteinaceus capsid. However, to date, the self …

Scaling properties of RNA as a randomly branching polymer

D Vaupotič, A Rosa, L Tubiana, A Božič - The Journal of Chemical …, 2023 - pubs.aip.org
Formation of base pairs between the nucleotides of a ribonucleic acid (RNA) sequence
gives rise to a complex and often highly branched RNA structure. While numerous studies …

Rna secondary structures regulate adsorption of fragments onto flat substrates

S Poblete, A Bozic, M Kanduc, R Podgornik… - ACS …, 2021 - ACS Publications
RNA is a functionally rich molecule with multilevel, hierarchical structures whose role in the
adsorption to molecular substrates is only beginning to be elucidated. Here, we introduce a …

Integration of Cypoviruses into polyhedrin matrix

OV Konevtsova, IY Golushko, R Podgornik… - Nanoscale …, 2023 - pubs.rsc.org
Unlike in other viruses, in Cypoviruses the genome is doubly protected since their
icosahedral capsids are embedded into a perfect polyhedrin crystal. Current experimental …

Molecular Dynamics Characterization of the Free and Encapsidated RNA2 of CCMV with the oxRNA Model

G Mattiotti, M Micheloni, L Petrolli… - Macromolecular …, 2024 - Wiley Online Library
The cowpea chlorotic mottle virus (CCMV) has emerged as a model system to assess the
balance between electrostatic and topological features of single‐stranded RNA viruses …

ANNaMo: Coarse-grained modeling for folding and assembly of RNA and DNA systems

F Tosti Guerra, E Poppleton, P Šulc… - The Journal of Chemical …, 2024 - pubs.aip.org
The folding of RNA and DNA strands plays crucial roles in biological systems and
bionanotechnology. However, studying these processes with high-resolution numerical …

[BOK][B] Single-stranded RNA phages: From molecular biology to nanotechnology

P Pumpens - 2020 - taylorfrancis.com
This is a comprehensive guide to single-stranded RNA phages (family Leviviridae), first
discovered in 1961. These phages played a unique role in early studies of molecular …

Impact of the RNA Binding Domain Localization of the Protein Shell on Virus Particle Stability

M Safdari, S Li, S Panahandeh… - arxiv preprint arxiv …, 2025 - arxiv.org
The encapsulation of polyanions, whether single-stranded RNAs or synthetic polymers, is
primarily driven by attractive electrostatic interactions between the positively charged …

nNxB: a new coarse-grained model for RNA and DNA nanotechnology

FT Guerra, E Poppleton, P Šulc, L Rovigatti - arxiv preprint arxiv …, 2023 - arxiv.org
The folding processes of RNA and DNA play crucial roles in biological systems and
nanotechnology. However, studying these processes with high-resolution models is beyond …