Mitral regurgitation (MR) is one of the most prevalent valve disorders and has numerous
aetiologies, including primary (organic) MR, due to underlying degenerative/structural mitral …

Background Despite advances in treatment, the increasing and ageing population makes
heart failure an important cause of morbidity and death worldwide. It is associated with high …

Abstract Aims The Valve Academic Research Consortium (VARC), founded in 2010, was
intended to (i) identify appropriate clinical endpoints and (ii) standardize definitions of these …

BACKGROUND: The ADHERE is designed to study characteristics, management, and
outcomes in a broad sample of patients hospitalized with acute decompensated heart …

Background The importance of heart failure with preserved ejection fraction is increasingly
recognized. We conducted a study to evaluate the epidemiologic features and outcomes of …

ContextA predictive model of mortality in heart failure may be useful for clinicians to improve
communication with and care of hospitalized patients. ObjectivesTo identify predictors of …

Heart failure (HF) and chronic obstructive pulmonary disease (COPD) are global epidemics
incurring significant morbidity and mortality. The combination presents many diagnostic …

Background Obstructive sleep apnea subjects the failing heart to adverse hemodynamic and
adrenergic loads and may thereby contribute to the progression of heart failure. We …

BACKGROUND: Identification of patients at high risk of death is critical for appropriate
management of patients and health care resources. The impact of repeated heart failure …

Objectives: The aim of this study was to assess the prognostic importance of left ventricular
ejection fraction (LVEF) in stable outpatients with heart failure (HF). Background: Although …