In comparison with 2D cell culture models, 3D spheroids are able to accurately mimic some
features of solid tumors, such as their spatial architecture, physiological responses …

Cancer stem cells (CSCs) are a sub-population of cells within cancer tissues with tumor
initiation, drug resistance and metastasis properties. CSCs also have been considered as …

Vasculogenic mimicry (VM) is a functional microcirculation pattern formed by aggressive
tumor cells and is related to the metastasis and poor prognosis of many cancer types …

Metastatic uveal melanoma remains incurable at present. We previously demonstrated that
loss of BAP1 gene expression in tumour cells triggers molecular mechanisms of …

Despite being widely used for basic and preclinical studies in dermatology, available animal
models only partly recapitulate human skin features, often leading to disappointing outputs …

Vasculogenic mimicry (VM) is a mechanism whereby cancer cells form microvascular
structures similar to three-dimensional channels to provide nutrients and oxygen to tumors …

Vasculogenic mimicry (VM) is a special vascular pattern in malignant tumors, which is
composed of highly aggressive tumor cells. This tumor cell‐mediated blood supply pattern is …

Vasculogenic mimicry (VM), defined as an endothelial cell independent alternative
mechanism of blood and nutrient supply by dysregulated tumor cells, is associated with poor …

Background Basal cell adhesion molecule (BCAM) is a laminin α5 (LAMA5) binding
membrane‐bound protein with a putative role in cancer. Besides full‐length BCAM1, an …

Mindin/spondin 2, an extracellular matrix (ECM) component that belongs to the
thrombospondin type 1 (TSR) class of molecules, plays prominent roles in the regulation of …