Trace amines and their receptors

RR Gainetdinov, MC Hoener, MD Berry - Pharmacological reviews, 2018 - Elsevier
Trace amines are endogenous compounds classically regarded as comprising β-
phenylethyalmine, p-tyramine, tryptamine, p-octopamine, and some of their metabolites …

Tyramine and octopamine: ruling behavior and metabolism

T Roeder - Annu. Rev. Entomol., 2005 - annualreviews.org
▪ Abstract Octopamine (OA) and tyramine (TA) are the invertebrate counterparts of the
vertebrate adrenergic transmitters. They are decarboxylation products of the amino acid …

IRE1 couples endoplasmic reticulum load to secretory capacity by processing the XBP-1 mRNA

M Calfon, H Zeng, F Urano, JH Till, SR Hubbard… - Nature, 2002 - nature.com
The unfolded protein response (UPR), caused by stress, matches the folding capacity of
endoplasmic reticulum (ER) to the load of client proteins in the organelle,. In yeast …

Neuromodulators signal through astrocytes to alter neural circuit activity and behaviour

Z Ma, T Stork, DE Bergles, MR Freeman - Nature, 2016 - nature.com
Astrocytes associate with synapses throughout the brain and express receptors for
neurotransmitters that can increase intracellular calcium (Ca2+),,. Astrocytic Ca2+ signalling …

[HTML][HTML] Tyramine functions independently of octopamine in the Caenorhabditis elegans nervous system

MJ Alkema, M Hunter-Ensor, N Ringstad, HR Horvitz - Neuron, 2005 - cell.com
Octopamine biosynthesis requires tyrosine decarboxylase to convert tyrosine into tyramine
and tyramine β-hydroxylase to convert tyramine into octopamine. We identified and …

Molecular and pharmacological properties of insect biogenic amine receptors: Lessons from Drosophila melanogaster and Apis mellifera

W Blenau, A Baumann - Archives of Insect Biochemistry and …, 2001 - Wiley Online Library
In the central nervous system (CNS) of both vertebrates and invertebrates, biogenic amines
are important neuroactive molecules. Physiologically, they can act as neurotransmitters …

Insect octopamine receptors: a new classification scheme based on studies of cloned Drosophila G-protein coupled receptors

PD Evans, B Maqueira - Invertebrate Neuroscience, 2005 - Springer
Insect octopamine receptors are G-protein coupled receptors. They can be coupled to
second messenger pathways to mediate either increases or decreases in intracellular cyclic …

[HTML][HTML] LIM homeobox gene-dependent expression of biogenic amine receptors in restricted regions of the C. elegans nervous system

EL Tsalik, T Niacaris, AS Wenick, K Pau, L Avery… - Developmental …, 2003 - Elsevier
Biogenic amines regulate a variety of behaviors. Their functions are predominantly mediated
through G-protein-coupled 7-transmembrane domain receptors (GPCR), 16 of which are …

Molecular response of Drosophila melanogaster tyramine receptor cascade to plant essential oils

EE Enan - Insect biochemistry and molecular biology, 2005 - Elsevier
This paper reports the role of the tyramine (TA) receptor cascade in the insecticidal activity of
plant essential oils. A TA receptor cDNA encoding a putative seven transmembrane domain …

Tyramine and octopamine have opposite effects on the locomotion of Drosophila larvae

S Saraswati, LE Fox, DR Soll, CF Wu - Journal of neurobiology, 2004 - Wiley Online Library
Biogenic amines are believed to play important roles in producing behaviors. Although
some biogenic amines have been extensively studied in both vertebrates and invertebrates …