Oxidative stress, implicated in the etiology of cancer, results from an imbalance in the
production of reactive oxygen species (ROS) and cell's own antioxidant defenses. ROS …

The generation of NO by the various NO synthases in normal and malignant tissues is
manifested by various biological effects that are involved in the regulation of cell survival …

Background: Quercetin, a major flavonol, wildly exists in plantage, which has been reported
to have an anti-apoptosis and anti-inflammation effects on vascular endothelial cells, but its …

Background Inflammation is critical in the pathophysiology of atherosclerosis (AS). The aim
of this study was to investigate the protective effect of salvianolic acid B (Sal B) on AS and to …

Several studies have implicated the role of Nitric Oxide (NO) in the regulation of tumor cell
behavior and have shown that NO either promotes or inhibits tumorigenesis. These …

Trefoil factor 1 (TFF1) is a tumor suppressor gene that encodes a peptide belonging to the
trefoil factor family of protease-resistant peptides. Although TFF1 expression is frequently …

Oxidative stress, implicated in the etiology of cancer, results from an imbalance in the
production of Reactive Oxygen Species (ROS) and cell's own antioxidant defenses. As a …

Evidence strongly supported a link between inflammation and cancer. Patients with colitis
have high risk for development of colon cancer. Nuclear factor-kappa B (NF-κB), partially …

The increased incidence of malignancies in elderly patients living in industrialized countries
has led to both identify the causes that alter the normal homeostatic balance in elderly and …

In the current review, we discuss the role of NF-kB and JAK/STAT signaling pathways and
their small molecule regulators in the therapy of inflammatory diseases. Considering …