Detecting liver cancer using cell-free DNA fragmentomes
ZH Foda, AV Annapragada, K Boyapati, DC Bruhm… - Cancer discovery, 2023 - AACR
Liver cancer is a major cause of cancer mortality worldwide. Screening individuals at high
risk, including those with cirrhosis and viral hepatitis, provides an avenue for improved …
risk, including those with cirrhosis and viral hepatitis, provides an avenue for improved …
HSPA6 and its role in cancers and other diseases
B Song, S Shen, S Fu, J Fu - Molecular Biology Reports, 2022 - Springer
Abstract Heat Shock Protein Family A (Hsp70) Member 6 (HSPA6)(Online Mendelian
Inheritance in Man: 140555) belongs to the HSP70 family and is a partially conserved …
Inheritance in Man: 140555) belongs to the HSP70 family and is a partially conserved …
Decoding the roles of heat shock proteins in liver cancer
C Sun, Q Pan, M Du, J Zheng, M Bai, W Sun - Cytokine & Growth Factor …, 2024 - Elsevier
Hepatocellular carcinoma (HCC) is one of the most common gastrointestinal malignancies,
characterized by insidious onset and high propensity for metastasis and recurrence. Apart …
characterized by insidious onset and high propensity for metastasis and recurrence. Apart …
Identification and partial characterization of new cell density-dependent nucleocytoplasmic shuttling proteins and open chromatin
K Li, Y Li, F Nakamura - Scientific Reports, 2023 - nature.com
The contact inhibition of proliferation (CIP) denotes the cell density-dependent inhibition of
growth, and the loss of CIP represents a hallmark of cancer. However, the mechanism by …
growth, and the loss of CIP represents a hallmark of cancer. However, the mechanism by …
Autophagy, molecular chaperones, and unfolded protein response as promoters of tumor recurrence
Tumor recurrence is a paradoxical function of a machinery, whereby a small proportion of
the cancer cell population enters a resistant, dormant state, persists long-term in this …
the cancer cell population enters a resistant, dormant state, persists long-term in this …
TEAD4 as an Oncogene and a Mitochondrial Modulator
SC Hsu, CY Lin, YY Lin, CC Collins… - Frontiers in Cell and …, 2022 - frontiersin.org
TEAD4 (TEA Domain Transcription Factor 4) is well recognized as the DNA-anchor protein
of YAP transcription complex, which is modulated by Hippo, a highly conserved pathway in …
of YAP transcription complex, which is modulated by Hippo, a highly conserved pathway in …
TEAD4: A key regulator of tumor metastasis and chemoresistance-Mechanisms and therapeutic implications
M Liu, W Hu, X Meng, B Wang - … et Biophysica Acta (BBA)-Reviews on …, 2024 - Elsevier
Cancer metastasis is a complex process influenced by various factors, including epithelial-
mesenchymal transition (EMT), tumor cell proliferation, tumor microenvironment, and cellular …
mesenchymal transition (EMT), tumor cell proliferation, tumor microenvironment, and cellular …
A three-gene signature reveals changes in the tumor immune microenvironment in the progression from NAFLD to HCC
L Liu, H Tang, K Wang, J Liu, N Luo, G ** - Scientific Reports, 2023 - nature.com
Hepatocellular carcinoma (HCC) is one of the most dangerous malignant tumors. The
incidence rates of obesity related NAFLD and NASH are increasing year by year, and they …
incidence rates of obesity related NAFLD and NASH are increasing year by year, and they …
Lnc-uc. 147 is associated with disease stage of liver, gastric, and renal cancer
AC Rodrigues, EP Zambalde, DL Bellan, ES Trindade… - Biomolecules, 2023 - mdpi.com
Lnc-uc. 147, a long non-coding RNA derived from a transcribed ultraconserved region (T-
UCR), was previously evidenced in breast cancer. However, the role of this region in other …
UCR), was previously evidenced in breast cancer. However, the role of this region in other …
Knockdown of HSP110 attenuates hypoxia-induced pulmonary hypertension in mice through suppression of YAP/TAZ-TEAD4 pathway
H Liu, S Zhang, Y Liu, J Ma, W Chen, T Yin, T Li… - Respiratory …, 2022 - Springer
Background Pulmonary hypertension (PH) is a progressive and fatal cardiopulmonary
disease characterized by pulmonary vascular remodeling and increased pulmonary …
disease characterized by pulmonary vascular remodeling and increased pulmonary …