Insulin resistance is a main determinant in the development of type 2 diabetes mellitus and a
major cause of morbidity and mortality. The circadian timing system consists of a central …

Lipids play important roles in energy metabolism along with diverse aspects of biological
membrane structure, signaling and other functions. Perturbations of lipid metabolism are …

Melatonin is a ubiquitous molecule present in almost every live being from bacteria to
humans. In vertebrates, besides being produced in peripheral tissues and acting as an …

Despite considerable advances in the past few years, obesity and type 2 diabetes mellitus
(T2DM) remain two major challenges for public health systems globally. In the past 9 years …

The circadian system is composed of coupled endogenous oscillators that allow living
beings, including humans, to anticipate and adapt to daily changes in their environment. In …

The circadian clock exerts an important role in systemic homeostasis as it acts a keeper of
time for the organism. The synchrony between the daily challenges imposed by the …

Circadian regulation of transcriptional processes has a broad impact on cell metabolism.
Here, we compared the diurnal transcriptome of human skeletal muscle conducted on serial …

The circadian clock is a biological mechanism that dictates an array of rhythmic
physiological processes. Virtually all cells contain a functional clock whose disruption results …

Cardiovascular diseases (CVD) are among the leading causes of death worldwide. Many
lines of evidence suggest that the disturbances in circadian rhythm are responsible for the …

Nutrient metabolism is under circadian regulation. Disruption of circadian rhythms by
lifestyle and behavioral choices such as work schedules, eating patterns, and social jetlag …