A subject of extensive study in evolutionary theory has been the issue of how neutral,
redundant copies can be maintained in the genome for long periods of time. Concurrently …

Gene duplications and their subsequent divergence play an important part in the evolution
of novel gene functions. Several models for the emergence, maintenance and evolution of …

Polyploidy is observed across the tree of life, yet its influence on evolution remains
incompletely understood,,,. Polyploidy, usually whole-genome duplication, is proposed to …

Gene duplication provides raw material for functional innovation. Recent advances have
shed light on two fundamental questions regarding gene duplication: which genes tend to …

Identifying the mechanisms of eukaryotic genome evolution by comparative genomics is
often complicated by the multiplicity of events that have taken place throughout the history of …

The growth rate‐dependent regulation of cell size, ribosomal content, and metabolic
efficiency follows a common pattern in unicellular organisms: with increasing growth rates …

Examples of extrachromosomal circular DNAs (eccDNAs) are found in many organisms, but
their impact on genetic variation at the genome scale has not been investigated. We …

Genome data have revealed great variation in the numbers of genes in different organisms,
which indicates that there is a fundamental process of genome evolution: the origin of new …

Changes in DNA copy number, whether confined to specific genes or affecting whole
chromosomes, have been identified as causes of diseases and developmental …

Background Gene duplications have a major role in the evolution of new biological
functions. Theoretical studies often assume that a duplication per se is selectively neutral …