Acinetobacter baumannii is regarded as a life-threatening pathogen associated with
community-acquired and nosocomial infections, mainly pneumonia. The rise in the number …

Posttranslational modifications (PTMs) regulate protein functions and interactions. ADP-
ribosylation is a PTM, in which ADP-ribosyltransferases use nicotinamide adenine …

Abstract TADB 3.0 (https://bioinfo-mml. sjtu. edu. cn/TADB3/) is an updated database that
provides comprehensive information on bacterial types I to VIII toxin–antitoxin (TA) loci …

Abstract TADB2. 0 (http://bioinfo-mml. sjtu. edu. cn/TADB2/) is an updated database that
provides comprehensive information about bacterial type II toxin–antitoxin (TA) loci …

After the first discovery in the 1980s in F-plasmids as a plasmid maintenance system, a
myriad of toxin-antitoxin (TA) systems has been identified in bacterial chromosomes and …

Chronic respiratory diseases including chronic rhinosinusitis, otitis media, asthma, cystic
fibrosis, non-CF bronchiectasis, and chronic obstructive pulmonary disease are a major …

Toxin-antitoxin (TA) modules are ubiquitous gene loci among bacteria and are comprised of
a toxin part and its cognate antitoxin part. Under normal physiological conditions, antitoxin …

Targeted killing of pathogenic bacteria without harming beneficial members of host
microbiota holds promise as a strategy to cure disease and limit both antimicrobial-related …

Biological neutralization represents a general strategy that deploys therapeutic agents to
bind with harmful molecules or infectious pathogens, block their bioactivity, and thus prevent …

Acetylation is a posttranslational modification conserved in all domains of life that is carried
out by N-acetyltransferases. While acetylation can occur on N α-amino groups, this review …