Technology of deep brain stimulation: current status and future directions
Deep brain stimulation (DBS) is a neurosurgical procedure that allows targeted circuit-based
neuromodulation. DBS is a standard of care in Parkinson disease, essential tremor and …
neuromodulation. DBS is a standard of care in Parkinson disease, essential tremor and …
Cycles in epilepsy
Epilepsy is among the most dynamic disorders in neurology. A canonical view holds that
seizures, the characteristic sign of epilepsy, occur at random, but, for centuries, humans …
seizures, the characteristic sign of epilepsy, occur at random, but, for centuries, humans …
Long-term wireless streaming of neural recordings for circuit discovery and adaptive stimulation in individuals with Parkinson's disease
Neural recordings using invasive devices in humans can elucidate the circuits underlying
brain disorders, but have so far been limited to short recordings from externalized brain …
brain disorders, but have so far been limited to short recordings from externalized brain …
A spinal cord neuroprosthesis for locomotor deficits due to Parkinson's disease
People with late-stage Parkinson's disease (PD) often suffer from debilitating locomotor
deficits that are resistant to currently available therapies. To alleviate these deficits, we …
deficits that are resistant to currently available therapies. To alleviate these deficits, we …
Emerging technologies for improved deep brain stimulation
Deep brain stimulation (DBS) is an effective treatment for common movement disorders and
has been used to modulate neural activity through delivery of electrical stimulation to key …
has been used to modulate neural activity through delivery of electrical stimulation to key …
Long-term ecological assessment of intracranial electrophysiology synchronized to behavioral markers in obsessive-compulsive disorder
Detection of neural signatures related to pathological behavioral states could enable
adaptive deep brain stimulation (DBS), a potential strategy for improving efficacy of DBS for …
adaptive deep brain stimulation (DBS), a potential strategy for improving efficacy of DBS for …
Seizure diaries and forecasting with wearables: epilepsy monitoring outside the clinic
It is a major challenge in clinical epilepsy to diagnose and treat a disease characterized by
infrequent seizures based on patient or caregiver reports and limited duration clinical …
infrequent seizures based on patient or caregiver reports and limited duration clinical …
A wearable platform for closed-loop stimulation and recording of single-neuron and local field potential activity in freely moving humans
U Topalovic, S Barclay, C Ling, A Alzuhair, W Yu… - Nature …, 2023 - nature.com
Advances in technologies that can record and stimulate deep brain activity in humans have
led to impactful discoveries within the field of neuroscience and contributed to the …
led to impactful discoveries within the field of neuroscience and contributed to the …