Sepsis is a deadly inflammatory syndrome caused by an exaggerated immune response to
infection. Much has been focused on host response to pathogens mediated through the …

Abstract Pandemic coronavirus disease 2019 (COVID-19) is caused by severe acute
respiratory syndrome coronavirus 2 (SARS-CoV-2) and poses an unprecedented challenge …

Sepsis is a life-threatening clinical syndrome characterized by multiorgan dysfunction
caused by a dysregulated or over-reactive host response to infection. During sepsis, the …

Acute lung injury (ALI) is a heterogeneous inflammatory condition associated with high
morbidity and mortality. Neutrophils play a key role in the development of different forms of …

Precision oncology is predicated upon the ability to detect specific actionable genomic
alterations and to monitor their adaptive evolution during treatment to counter resistance …

Thrombosis is a common consequence of infection that is associated with poor patient
outcome. Nevertheless, the mechanisms by which infection-associated thrombosis is …

Necrosis is an overarching term that describes cell death modalities caused by (extreme)
adverse conditions in which cells lose structural integrity. A guaranteed consequence of …

Beyond their role in hemostasis and thrombosis, platelets are increasingly recognized as
key regulators of the inflammatory response under sterile and infectious conditions. Both …

Sepsis is a prevalent disease that has alarmingly high mortality rates and, for several
survivors, long-term morbidity. The modern definition of sepsis is an aberrant host response …

Venous thrombosis (VT), a leading cause of morbidity and mortality worldwide, has recently
been linked to neutrophil activation and release of neutrophil extracellular traps (NETs) via a …