Nowadays, the vastly increasing demand for novel biotechnological products is supported
by the continuous development of biocatalytic applications that provide sustainable green …

With recent developments in X-ray sources, instrumentation and data-analysis tools, time-
resolved crystallographic experiments, which were originally the preserve of a few expert …

Thanks to recent technological advances in X-ray and micro-electron diffraction and solid-
state NMR, structural information can be obtained by using much smaller crystals. Thus …

Serial crystallography at conventional synchrotron light sources (SSX) offers the possibility
to routinely collect data at room temperature using micrometre-sized crystals of biological …

Macromolecular crystallography is a well established method in the field of structural biology
and has led to the majority of known protein structures to date. After focusing on static …

The development of x-ray free electron laser (XFEL) light sources and serial crystallography
methodologies has led to a revolution in protein crystallography, enabling the determination …

An estimated half of all proteins contain a metal, with these being essential for a tremendous
variety of biological functions. X-ray crystallography is the major method for obtaining …

The rapid preparation of homogeneous suspensions of micro-or nanocrystals is a crucial
step in serial crystallography. We show how additives, such as the crystallophore (TbXo4) …

Serial crystallography requires large numbers of microcrystals and robust strategies to
rapidly apply substrates to initiate reactions in time-resolved studies. Here, we report the use …

The cytochrome P450 monooxygenases (CYPs) are a class of heme‐thiolate enzymes that
insert oxygen into unactivated C− H bonds. These enzymes can be converted into …