Interstitial lung diseases

M Wijsenbeek, A Suzuki, TM Maher - The Lancet, 2022 - thelancet.com
Over 200 interstitial lung diseases, from ultra rare to relatively common, are recognised.
Most interstitial lung diseases are characterised by inflammation or fibrosis within the …

Idiopathic pulmonary fibrosis: Disease mechanisms and drug development

P Spagnolo, JA Kropski, MG Jones, JS Lee… - Pharmacology & …, 2021 - Elsevier
Idiopathic pulmonary fibrosis (IPF) is a chronic progressive disease of unknown cause
characterized by relentless scarring of the lung parenchyma leading to reduced quality of life …

Idiopathic pulmonary fibrosis (an update) and progressive pulmonary fibrosis in adults: an official ATS/ERS/JRS/ALAT clinical practice guideline

G Raghu, M Remy-Jardin, L Richeldi… - American Journal of …, 2022 - atsjournals.org
Background: This American Thoracic Society, European Respiratory Society, Japanese
Respiratory Society, and Asociación Latinoamericana de Tórax guideline updates prior …

Diagnosis of hypersensitivity pneumonitis in adults: an official ATS/JRS/ALAT clinical practice guideline

G Raghu, M Remy-Jardin, CJ Ryerson… - American journal of …, 2020 - atsjournals.org
Background: This guideline addresses the diagnosis of hypersensitivity pneumonitis (HP). It
represents a collaborative effort among the American Thoracic Society, Japanese …

[HTML][HTML] Nintedanib in progressive fibrosing interstitial lung diseases

KR Flaherty, AU Wells, V Cottin… - … England Journal of …, 2019 - Mass Medical Soc
Background Preclinical data have suggested that nintedanib, an intracellular inhibitor of
tyrosine kinases, inhibits processes involved in the progression of lung fibrosis. Although the …

Single-cell RNA-seq reveals ectopic and aberrant lung-resident cell populations in idiopathic pulmonary fibrosis

TS Adams, JC Schupp, S Poli, EA Ayaub… - Science …, 2020 - science.org
We provide a single-cell atlas of idiopathic pulmonary fibrosis (IPF), a fatal interstitial lung
disease, by profiling 312,928 cells from 32 IPF, 28 smoker and nonsmoker controls, and 18 …

Interstitial lung abnormalities detected incidentally on CT: a Position Paper from the Fleischner Society

H Hatabu, GM Hunninghake, L Richeldi… - The lancet Respiratory …, 2020 - thelancet.com
The term interstitial lung abnormalities refers to specific CT findings that are potentially
compatible with interstitial lung disease in patients without clinical suspicion of the disease …

Trial of a preferential phosphodiesterase 4B inhibitor for idiopathic pulmonary fibrosis

L Richeldi, A Azuma, V Cottin… - … England Journal of …, 2022 - Mass Medical Soc
Abstract Background Phosphodiesterase 4 (PDE4) inhibition is associated with
antiinflammatory and antifibrotic effects that may be beneficial in patients with idiopathic …

Spectrum of fibrotic lung diseases

M Wijsenbeek, V Cottin - New England Journal of Medicine, 2020 - Mass Medical Soc
Pulmonary Fibrotic Diseases This review covers fibrotic pulmonary diseases. Although
idiopathic pulmonary fibrosis is very common, the review focuses mainly on fibrotic diseases …

2023 American College of Rheumatology (ACR)/American College of Chest Physicians (CHEST) guideline for the screening and monitoring of interstitial lung disease …

SR Johnson, EJ Bernstein, MB Bolster… - Arthritis Care & …, 2024 - Wiley Online Library
Objective We provide evidence‐based recommendations regarding screening for interstitial
lung disease (ILD) and the monitoring for ILD progression in people with systemic …