Leukocyte migration from the vascular compartment is critical for normal lymphocyte
recirculation in specific tissues and immune response in inflammatory locations. Leukocyte …

Remarkable progress in ageing research has been achieved over the past decades.
General perceptions and experimental evidence pinpoint that the decline of physical …

The vascular cellular adhesion molecule-1 (VCAM-1) is a protein that canonically
participates in the adhesion and transmigration of leukocytes to the interstitium during …

Aging is a universal process that can cause diminished function of organs and various
diseases. The most striking consequences of aging can be seen visibly on the skin, which …

Background: Quercetin, a major flavonol, wildly exists in plantage, which has been reported
to have an anti-apoptosis and anti-inflammation effects on vascular endothelial cells, but its …

A central function of the vascular endothelium is to serve as a barrier between the blood and
the surrounding tissue of the body. At the same time, solutes and cells have to pass the …

Sepsis accounts for nearly 700 000 deaths in Europe annually and is caused by an
overwhelming host response to infection resulting in organ failure. The endothelium is an …

Sepsis is a disease characterized by multiple organ failure caused by immune
hyperactivation and cytokine storms. Studies have shown that the incidence of sepsis in …

Sepsis, a prevalent critical condition in clinics, continues to be the leading cause of death
from infections and a global healthcare issue. Among the organs susceptible to the harmful …

Current COVID-19 pandemic poses an unprecedented threat to global health and
healthcare systems. The most amount of the death toll is accounted by old people affected …