Interpreting biologically informed neural networks for enhanced proteomic biomarker discovery and pathway analysis
The incorporation of machine learning methods into proteomics workflows improves the
identification of disease-relevant biomarkers and biological pathways. However, machine …
identification of disease-relevant biomarkers and biological pathways. However, machine …
Unravelling potential biomarkers for acute and chronic brucellosis through proteomic and bioinformatic approaches
Y Yang, K Qiao, Y Yu, Y Zong, C Liu… - Frontiers in Cellular and …, 2023 - frontiersin.org
Introduction This study aimed to identify biomarkers for acute and chronic brucellosis using
advanced proteomic and bioinformatic methods. Methods Blood samples from individuals …
advanced proteomic and bioinformatic methods. Methods Blood samples from individuals …
Population scale proteomics enables adaptive digital twin modelling in sepsis
Sepsis is one of the leading causes of mortality in the world. Currently, the heterogeneity of
sepsis makes it challenging to determine the molecular mechanisms that define the …
sepsis makes it challenging to determine the molecular mechanisms that define the …
Explainable machine learning for the identification of proteome states via the data processing kitchen sink
The application of machine learning algorithms to facilitate the understanding of changes in
proteome states has emerged as a promising methodology in proteomics research …
proteome states has emerged as a promising methodology in proteomics research …
Assessment of false discovery rate control in tandem mass spectrometry analysis using entrapment
A pressing statistical challenge in the field of mass spectrometry proteomics is how to assess
whether a given software tool provides accurate error control. Each software tool for …
whether a given software tool provides accurate error control. Each software tool for …
DeepBINN: A tailored biologically-informed neural network for robust biomarker identification
J Meirer, LD Wittwer, V Revol… - 2024 11th IEEE Swiss …, 2024 - ieeexplore.ieee.org
Biologically-informed neural networks (BINNs) have recently been proposed to aid in
identifying disease-relevant biomarkers and biological pathways using deep neural …
identifying disease-relevant biomarkers and biological pathways using deep neural …