The role of protein corona on nanodrugs for organ-targeting and its prospects of application

S Wang, J Zhang, H Zhou, YC Lu, X **, L Luo… - Journal of Controlled …, 2023 - Elsevier
Nowadays, nanodrugs become a hotspot in the high-end medical field. They have the ability
to deliver drugs to reach their destination more effectively due to their unique properties and …

The journey of a drug-carrier in the body: an anatomo-physiological perspective

N Bertrand, JC Leroux - Journal of controlled release, 2012 - Elsevier
Recent advances in chemistry and material sciences have witnessed the emergence of an
increasing number of novel and complex nanosized carriers for the delivery of drugs and …

Brown fat activation reduces hypercholesterolaemia and protects from atherosclerosis development

JFP Berbée, MR Boon, PPSJ Khedoe, A Bartelt… - Nature …, 2015 - nature.com
Brown adipose tissue (BAT) combusts high amounts of fatty acids, thereby lowering plasma
triglyceride levels and reducing obesity. However, the precise role of BAT in plasma …

Interactions of nanomaterials and biological systems: Implications to personalized nanomedicine

XQ Zhang, X Xu, N Bertrand, E Pridgen… - Advanced drug delivery …, 2012 - Elsevier
The application of nanotechnology to personalized medicine provides an unprecedented
opportunity to improve the treatment of many diseases. Nanomaterials offer several …

Controlling the stealth effect of nanocarriers through understanding the protein corona

S Schöttler, K Landfester… - Angewandte Chemie …, 2016 - Wiley Online Library
The past decade has seen a significant increase in interest in the use of polymeric
nanocarriers in medical applications. In particular, when used as drug vectors in targeted …

Butyrate reduces appetite and activates brown adipose tissue via the gut-brain neural circuit

Z Li, CX Yi, S Katiraei, S Kooijman, E Zhou, CK Chung… - Gut, 2018 - gut.bmj.com
Objective Butyrate exerts metabolic benefits in mice and humans, the underlying
mechanisms being still unclear. We aimed to investigate the effect of butyrate on appetite …

Injectable lipid emulsions—advancements, opportunities and challenges

K Hippalgaonkar, S Majumdar, V Kansara - Aaps Pharmscitech, 2010 - Springer
Injectable lipid emulsions, for decades, have been clinically used as an energy source for
hospitalized patients by providing essential fatty acids and vitamins. Recent interest in …

Brown adipose tissue takes up plasma triglycerides mostly after lipolysis

PPSJ Khedoe, G Hoeke, S Kooijman, W Dijk… - Journal of lipid …, 2015 - jlr.org
Brown adipose tissue (BAT) produces heat by burning TGs that are stored within
intracellular lipid droplets and need to be replenished by the uptake of TG-derived FA from …

ApoAV reduces plasma triglycerides by inhibiting very low density lipoprotein-triglyceride (VLDL-TG) production and stimulating lipoprotein lipase-mediated VLDL-TG …

FG Schaap, PCN Rensen, PJ Voshol, C Vrins… - Journal of biological …, 2004 - jbc.org
ApoAV has been discovered recently as a novel modifier of triglyceride (TG) metabolism, but
the pathways involved are currently unknown. To gain insight into the function of apoAV …

Pharmacological treatment with FGF21 strongly improves plasma cholesterol metabolism to reduce atherosclerosis

C Liu, M Schönke, E Zhou, Z Li… - Cardiovascular …, 2022 - academic.oup.com
Aims Fibroblast growth factor (FGF) 21, a key regulator of energy metabolism, is currently
evaluated in humans for treatment of type 2 diabetes and non-alcoholic steatohepatitis …